Combined calcium and vitamin D supplementation reduces bone loss and fracture incidence in older men and women.

Combined calcium and vitamin D supplementation reduces bone loss and fracture incidence in older men and women.
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钙和维生素 D 联合补充可减少老年男性和女性的骨质流失和骨折发生率。

DOI:
10.1111/j.1753-4887.1998.tb01740.x
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发表时间:
2009
期刊:
影响因子:
6.1
通讯作者:
K. O’Brien
K. O’Brien
中科院分区:
医学2区
文献类型:
--
作者:
K. O’Brien

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最近对389名年龄在65岁以上的男性和女性进行了一项补充研究,以探讨钙和维生素D联合补充对非脊椎骨折发生率和骨量维持的影响。与安慰剂组相比,每日补充500毫克钙和700IU维生素D持续3年,适度减少了几个部位的骨丢失,并显著降低了非脊椎骨折的发生率。在老年男性和女性中,最佳的钙和维生素D摄入量可能是维持现有骨量和降低骨折风险的一种容易实施的策略。
A recent supplementation study of 389 men and women, over the age of 65 years was conducted to address the impact of combined calcium and vitamin D supplementation on nonvertebral fracture incidence and maintenance of bone mass. Daily supplementation with 500 mg calcium and 700 IU vitamin D for 3 years moderately reduced bone loss at several sites and significantly decreased the rate of nonvertebral fractures, compared with a placebo group. Optimal intake of both calcium and vitamin D may be an easily implemented strategy to maintain existing bone mass and reduce the risk of fracture in older men and women.
DOI: 10.1056/nejm199709043371003
发表时间: 1997-09-04
影响因子: 158.5
作者:
DawsonHughes, B;Harris, SS;Dallal, GE
通讯作者: Dallal, GE