Examining post-donation outcomes in Hispanic/Latinx living kidney donors in the United States: A systematic review.
Examining post-donation outcomes in Hispanic/Latinx living kidney donors in the United States: A systematic review.
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检查美国西班牙裔/拉丁裔活体肾脏捐赠者的捐赠后结果：一项系统性综述。
DOI：
10.1111/ajt.17017
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发表时间：
2022-07
影响因子：
8.8
通讯作者：
Purnell, Tanjala S.
中科院分区：
文献类型：
--
作者：
Alvarado, Flor;Cervantes, Carmen Elena;Crews, Deidra C.;Blanck, Jamie;Al Ammary, Fawaz;Ng, Derek K.;Purnell, Tanjala S.
关键词：
我们进行了一项系统的回顾，以评估拉美裔捐赠者的结果，并探索拉美裔族裔的特征。我们在PubMed、EMBASE和Scope上搜索到2021年10月。两名评价者独立筛选研究标题、摘要和全文；他们还定性地综合结果并独立评估纳入研究的质量。18项研究符合我们的纳入标准。研究样本规模从4007到143,750名捐赠者，平均年龄从37岁到54岁不等。研究的最长随访时间从供者肾切除围手术期到捐献后30年不等。在所有研究中，西班牙裔捐赠者占捐赠者总数的6%到21%。大多数研究报告了种族或种族和民族组合类别下的西班牙裔族裔。与非西班牙裔白人捐赠者相比，西班牙裔捐赠者捐献后死亡率、终末期肾脏疾病、心血管疾病、非妊娠相关住院或整个手术并发症的风险没有增加。与非西班牙裔白人捐赠者相比，大多数研究表明，西班牙裔捐赠者在肾脏切除后患糖尿病的风险更高；然而，关于捐赠后慢性肾脏疾病和高血压的风险，研究结果喜忧参半。未来的研究应该评估不同拉美裔捐献者群体中的文化、社会经济和地理差异，这可能进一步解释健康结果的差异。与非西班牙裔活体肾脏捐赠者相比，西班牙裔活体肾脏捐赠者不会增加捐赠后死亡率、终末期肾脏疾病、心血管疾病、非妊娠相关住院或围手术期并发症的风险，但患捐赠后糖尿病的风险更高。
We conducted a systematic review to assess outcomes in Hispanic donors and explore how Hispanic ethnicity was characterized. We searched PubMed, EMBASE, and Scopus through October 2021. Two reviewers independently screened study titles, abstracts, and full texts; they also qualitatively synthesized results and independently assessed quality of included studies. Eighteen studies met our inclusion criteria. Study sample sizes ranged from 4007 to 143,750 donors and mean age ranged from 37 to 54 years. Maximum follow‐up time of studies varied from a perioperative donor nephrectomy period to 30 years post‐donation. Hispanic donors ranged between 6% and 21% of the donor populations across studies. Most studies reported Hispanic ethnicity under race or a combined race and ethnicity category. Compared to non‐Hispanic White donors, Hispanic donors were not at increased risk for post‐donation mortality, end‐stage kidney disease, cardiovascular disease, non‐pregnancy‐related hospitalizations, or overall perioperative surgical complications. Compared to non‐Hispanic White donors, most studies showed Hispanic donors were at higher risk for diabetes mellitus following nephrectomy; however, mixed findings were seen regarding the risk for post‐donation chronic kidney disease and hypertension. Future studies should evaluate cultural, socioeconomic, and geographic differences within the heterogeneous Hispanic donor population, which may further explain variation in health outcomes. Hispanic compared to non‐Hispanic living kidney donors are not at increased risk for post‐donation mortality, end‐stage kidney disease, cardiovascular disease, non‐pregnancy‐related hospitalizations, or perioperative surgical complications, but are at higher risk of post‐donation diabetes.
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影响因子：
4.4
作者：
Alvaro, Eusebio M.;Siegel, Jason T.;Dominick, Alexander
通讯作者：
Dominick, Alexander
影响因子：
2.9
作者：
Davis, Connie L.
通讯作者：
Davis, Connie L.
影响因子：
5.4
作者：
Elfassy, Tali;Al Hazzouri, Adina Zeki;Schneiderman, Neil
通讯作者：
Schneiderman, Neil
影响因子：
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作者：
Friedman, Amy L.;Cheung, Kevin;Sosa, Julie Ann
通讯作者：
Sosa, Julie Ann
DOI：
10.1097/01.mnh.0000444822.25991.f6
发表时间：
2014-05
影响因子：
3.2
作者：
Crews DC;Liu Y;Boulware LE
通讯作者：
Boulware LE