Identification and localisation of the NB-LRR gene family within the potato genome.
Identification and localisation of the NB-LRR gene family within the potato genome.
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DOI:
10.1186/1471-2164-13-75
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发表时间:
2012-02-15
期刊:
影响因子:
4.4
通讯作者:
Hein I
中科院分区:
文献类型:
--
作者:
Jupe F;Pritchard L;Etherington GJ;Mackenzie K;Cock PJ;Wright F;Sharma SK;Bolser D;Bryan GJ;Jones JD;Hein I
The potato genome sequence derived from the Solanum tuberosum Group Phureja clone DM1-3 516 R44 provides unparalleled insight into the genome composition and organisation of this important crop. A key class of genes that comprises the vast majority of plant resistance (R) genes contains a nucleotide-binding and leucine-rich repeat domain, and is collectively known as NB-LRRs. As part of an effort to accelerate the process of functional R gene isolation, we performed an amino acid motif based search of the annotated potato genome and identified 438 NB-LRR type genes among the ~39,000 potato gene models. Of the predicted genes, 77 contain an N-terminal toll/interleukin 1 receptor (TIR)-like domain, and 107 of the remaining 361 non-TIR genes contain an N-terminal coiled-coil (CC) domain. Physical map positions were established for 370 predicted NB-LRR genes across all 12 potato chromosomes. The majority of NB-LRRs are physically organised within 63 identified clusters, of which 50 are homogeneous in that they contain NB-LRRs derived from a recent common ancestor. By establishing the phylogenetic and positional relationship of potato NB-LRRs, our analysis offers significant insight into the evolution of potato R genes. Furthermore, the data provide a blueprint for future efforts to identify and more rapidly clone functional NB-LRR genes from Solanum species.
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影响因子:
3
作者:
Bailey TL;Bodén M;Whitington T;Machanick P
通讯作者:
Machanick P
DOI:
10.1093/bioinformatics/btp163
发表时间:
2009-06-01
期刊:
Bioinformatics (Oxford, England)
影响因子:
--
作者:
Cock PJ;Antao T;Chang JT;Chapman BA;Cox CJ;Dalke A;Friedberg I;Hamelryck T;Kauff F;Wilczynski B;de Hoon MJ
通讯作者:
de Hoon MJ
影响因子:
7.2
作者:
Bendahmane, A;Querci, M;Baulcombe, DC
通讯作者:
Baulcombe, DC
影响因子:
3.9
作者:
Cannon, SB;Zhu, HY;Young, ND
通讯作者:
Young, ND
影响因子:
7.2
作者:
Huang, SW;van der Vossen, EAG;Visser, RGF
通讯作者:
Visser, RGF