Rapid single scan ramped hybrid-encoding for bicomponent T2* mapping in a human knee joint: A feasibility study.
Rapid single scan ramped hybrid-encoding for bicomponent T2* mapping in a human knee joint: A feasibility study.
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DOI：
10.1002/nbm.4391
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发表时间：
2020-11
影响因子：
2.9
通讯作者：
Kijowski R
中科院分区：
文献类型：
--
作者：
Jang H;McMillan AB;Ma Y;Jerban S;Chang EY;Du J;Kijowski R
本研究的目的是确定使用单次扫描斜坡混合编码（RHE）方法对人膝关节进行快速双组分T2*分析的可行性。
所提出的方法利用RHE在单次扫描中，在40微秒到30毫秒之间的16个不同回波时间获取超短回波时间（UTE）图像以及后续的梯度回波图像。在所提出的RHE技术中，UTE成像之后是14次梯度回波成像，其中通过过采样单点成像（SPI）编码在首次读出期间获得了额外的UTE图像。在3T场强下，对来自6名捐赠者的人体尸体膝关节以及来自4名健康志愿者的活体膝关节进行了单次扫描RHE方法，扫描时间为9分钟。使用双组分信号模型来表征短T2*和长T2*水组分。计算了髌腱、前交叉韧带（ACL）、后交叉韧带（PCL）和半月板的平均双组分T2*参数。
在实验结果中，RHE技术提供了肌腱、ACL、PCL和半月板的双组分T2*参数估计值，这些值与文献中先前报道的值相似。
总之，所提出的单次扫描RHE技术能够对人膝关节进行快速双组分T2*分析，总扫描时间少于9分钟。
The purpose of this study is to determine the feasibility of using a single scan ramped hybrid encoding (RHE) method for rapid bicomponent T2* analysis of the human knee joint. The proposed method utilizes RHE to acquire UTE and subsequent gradient echo images at 16 different echo times ranging between 40μs and 30ms in a single scan. In the proposed RHE technique, UTE imaging was followed by 14 gradient recalled echo imaging, where an additional UTE image was obtained within the first readout by oversampling single point imaging (SPI) encoding. The single scan RHE method with 9-minute scan time was performed on human cadaveric knee joints from six donors and in vivo knee joints from four healthy volunteers at 3T. A bicomponent signal model was used to characterize the short T2* and long T2* water components. Mean bicomponent T2* parameters for patellar tendon, anterior cruciate ligament (ACL), posterior cruciate ligament (PCL), and meniscus were calculated. In the experimental results, the RHE technique provided bicomponent T2* parameter estimations of tendon, ACL, PCL, and meniscus which were similar to previously reported values in the literature. In conclusion, the proposed single scan RHE technique provides rapid bicomponent T2* analysis of the human knee joint with a total scan time less than 9 min.
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影响因子：
3.3
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通讯作者：
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