Revisiting the role of heterochromatin protein 1 in DNA repair.

Revisiting the role of heterochromatin protein 1 in DNA repair.
复制标题

DOI:
10.1083/jcb.200904033
复制
发表时间:
2009-05-18
期刊:
The Journal of cell biology
影响因子:
--
通讯作者:
Yokomori K
Yokomori K
中科院分区:
其他
文献类型:
--
作者:
Ball AR Jr;Yokomori K

文献摘要

参考文献

被引文献

相似文献

异染色质蛋白1 (HP1)是一个保守因子,对异染色质组织和基因沉默至关重要。它通过与H3K9me(组蛋白H3的甲基化赖氨酸9残基)的直接相互作用被招募到染色质中,H3K9me是沉默染色质的表观遗传标记。现在,Luijsterburg等人(Luijsterburg, m.s., C. Dinant, H. Lans, J. Stap, E. Wiernasz, S. Lagerwerf, D.O. Warmerdam, M. Lindh, M.C. Brink, J.W. Dobrucki等,2009)。J.细胞生物学,185:577-586)揭示了HP1在DNA损伤反应中的一个新的不依赖于h3k9me的作用,这与Ayoub等人最近报道的不同(Ayoub, N., ad . Jeyasekharan, J.A. Bernal和A.R. Venkitaraman, 2008)。大自然。453:682 - 686)。
Heterochromatin protein 1 (HP1) is a conserved factor critical for heterochromatin organization and gene silencing. It is recruited to chromatin by its direct interaction with H3K9me (methylated lysine 9 residue of histone H3), an epigenetic mark for silenced chromatin. Now, Luijsterburg et al. (Luijsterburg, M.S., C. Dinant, H. Lans, J. Stap, E. Wiernasz, S. Lagerwerf, D.O. Warmerdam, M. Lindh, M.C. Brink, J.W. Dobrucki, et al. 2009. J. Cell Biol. 185:577–586) reveal a new H3K9me-independent role for HP1 in the DNA damage response, which is distinct from the one recently reported by Ayoub et al. (Ayoub, N., A.D. Jeyasekharan, J.A. Bernal, and A.R. Venkitaraman. 2008. Nature. 453:682–686).
DOI: 10.1016/s1097-2765(01)00218-0
发表时间: 2001-04-01
期刊: MOLECULAR CELL
影响因子: 16
作者:
Nielsen, AL;Oulad-Abdelghani, M;Losson, R
通讯作者: Losson, R
DOI: 10.1083/jcb.200804041
发表时间: 2008-11-17
期刊: The Journal of cell biology
影响因子: --
作者:
Aucott R;Bullwinkel J;Yu Y;Shi W;Billur M;Brown JP;Menzel U;Kioussis D;Wang G;Reisert I;Weimer J;Pandita RK;Sharma GG;Pandita TK;Fundele R;Singh PB
通讯作者: Singh PB
DOI: 10.1016/j.dnarep.2008.11.007
发表时间: 2009-02-01
期刊: DNA REPAIR
影响因子: 3.8
作者:
Zhu, Qianzheng;Wani, Gulzar;Arab, Hany H.;Ei-Mahdy, Mohamed A.;Ray, Alo;Wani, Altaf A.
通讯作者: Wani, Altaf A.
DOI: 10.1038/nature06875
发表时间: 2008-05-29
期刊: NATURE
影响因子: 64.8
作者:
Ayoub, Nabieh;Jeyasekharan, Anand D.;Venkitaraman, Ashok R.
通讯作者: Venkitaraman, Ashok R.
DOI: 10.1093/nar/gkp221
发表时间: 2009-05
影响因子: 14.9
作者:
Kong X;Mohanty SK;Stephens J;Heale JT;Gomez-Godinez V;Shi LZ;Kim JS;Yokomori K;Berns MW
通讯作者: Berns MW