Mortality, Intensive Care Unit Admission, and Intubation among Hospitalized Patients with COVID-19: A One-Year Retrospective Study in Jordan.
Mortality, Intensive Care Unit Admission, and Intubation among Hospitalized Patients with COVID-19: A One-Year Retrospective Study in Jordan.
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DOI：
10.3390/jcm12072651
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发表时间：
2023-04-02
影响因子：
3.9
通讯作者：
Obeidat N
中科院分区：
文献类型：
--
作者：
Al Oweidat K;Al-Amer R;Saleh MY;Albtoosh AS;Toubasi AA;Ribie MK;Hasuneh MM;Alfaqheri DL;Alshurafa AH;Ribie M;Ali AM;Obeidat N
COVID-19是一场公共卫生危机，已造成大量死亡，住院人数增加，并导致住院时间延长。本研究旨在确定约旦患者中与COVID-19死亡率、重症监护病房入院、插管和住院时间相关的因素。这是一项为期一年的回顾性研究，纳入了约旦大学医院的745名COVID-19患者。使用编码手册从患者的医疗记录中收集有关患者的人口统计学、临床和合并症、影像学、实验室参数、死亡率、重症监护病房住院（ICU）和插管的数据。数据显示，新冠肺炎相关死亡率、ICU住院率和有创插管率分别为23.0%、28.3%和10.8%。慢性肾脏疾病（CKD）、肌钙蛋白、乳酸脱氢酶（LDH）和氧饱和度<90%与死亡率显著相关。与ICU入院显著相关的变量是心力衰竭和瑞德西韦的使用。然而，氧饱和度<90%和胃肠道（GI）症状是与有创插管相关的唯一变量。这项研究的结果表明，与研究相关的健康结果可用于预测COVID-19的严重程度，它们可以为未来的研究提供信息，旨在确定罹患COVID-19并发症风险较高的特定人群。
COVID-19 is a public health crisis that has caused numerous deaths, necessitated an increased number of hospital admissions, and led to extended inpatient stays. This study aimed to identify the factors associated with COVID-19 mortality, intensive care unit admission, intubation, and length of hospital stay among Jordanian patients. This was a one-year retrospective study of 745 COVID-19 patients admitted to Jordan University Hospital. Data regarding the patients’ demographics, clinical and co-morbid conditions, imaging, laboratory parameters, mortality, intensive care unit admission (ICU), and intubation were collected from their medical records using a coding manual. The data revealed that the overall rates of COVID-19-related mortality, ICU admission, and invasive intubation were 23.0%, 28.3%, and 10.8%, respectively. Chronic kidney disease (CKD), troponin, lactate dehydrogenase (LDH), and O2 saturation <90% were significantly associated with the mortality rate. The variables that were significantly associated with ICU admission were heart failure and the use of remdesivir. However, O2 saturation <90% and gastrointestinal (GI) symptoms were the only variables associated with invasive intubation. The findings of this study suggest that study-related health outcomes can be used to predict the severity of COVID-19, and they can inform future research aiming to identify specific populations who are at a higher risk of COVID-19 complications.
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DOI：
10.1097/00002060-199102001-00008
发表时间：
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影响因子：
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作者：
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通讯作者：
DAUM, MC
DOI：
10.3138/jammi-2020-0030
发表时间：
2020-12-01
期刊：
Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada
影响因子：
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作者：
Byambasuren, Oyungerel;Cardona, Magnolia;Glasziou, Paul
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