Time-reversed adapted-perturbation (TRAP) optical focusing onto dynamic objects inside scattering media.

Time-reversed adapted-perturbation (TRAP) optical focusing onto dynamic objects inside scattering media.
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DOI:
10.1038/nphoton.2014.251
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发表时间:
2014-12
期刊:
影响因子:
35
通讯作者:
--
中科院分区:
物理与天体物理1区
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长期以来,人们一直在寻求在散射介质内引导和聚焦光的能力,以实现多种应用。要在散射介质中形成光学焦点,目前唯一可行的策略是用植入的或虚拟的引导星来引导光子,这可能会带来不便,限制了潜在的应用。在这里,我们报告了一种利用本征动力学作为导星来聚焦散射介质中的光的方案。通过自适应地对散射光的扰动分量进行时间反转,我们证明了将光聚焦到微扰的原点是可能的。利用这种方法,我们演示了非侵入性的动态光聚焦到运动目标上,以及对被高散射介质遮挡的时变目标的成像。预期的应用包括肿瘤血管新生血管的成像和光消融,以及其他生物医学用途。
The ability to steer and focus light inside scattering media has long been sought for a multitude of applications. To form optical foci inside scattering media, the only feasible strategy at present is to guide photons by using either implanted or virtual guide stars, which can be inconvenient and limits potential applications. Here, we report a scheme for focusing light inside scattering media by employing intrinsic dynamics as guide stars. By time-reversing the perturbed component of the scattered light adaptively, we show that it is possible to focus light to the origin of the perturbation. Using the approach, we demonstrate non-invasive dynamic light focusing onto moving targets and imaging of a time-variant object obscured by highly scattering media. Anticipated applications include imaging and photoablation of angiogenic vessels in tumours as well as other biomedical uses.
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