High level of tubulin microheterogeneity in the mouse brain
High level of tubulin microheterogeneity in the mouse brain
复制标题
小鼠大脑中高水平的微管蛋白微异质性
DOI：
10.1016/0304-3940(82)90041-6
复制
发表时间：
1982
影响因子：
2.5
通讯作者：
C. Jeantet
中科院分区：
文献类型：
--
作者：
A. Wolff;P. Denoulet;C. Jeantet
使用高分辨率等电聚焦方法，我们已经证明了高水平的微管蛋白的异质性在小鼠脑中：21 isotubulins被确定。通过测定表观分子量和分析每种异微管蛋白的肽图，我们鉴定了7个α和14个β微管蛋白亚基。此外，在大脑发育过程中这种微管蛋白群体的变化得到了证实;特别是，在出生后开始时观察到β异微管蛋白数量的增加。
Using a high resolution isoelectric focusing method, we have demonstrated a high level of tubulin heterogeneity in mouse brain: 21 isotubulins were identified. Determination of the apparent molecular weight and analysis of the peptide map of each isotubulin species allowed us to identify 7 α and 14 β tubulin subunits. Furthermore, variations in this tubulin population during brain development were confirmed; in particular, an increase in the number of β isotubulins was observed at the beginning of the postnatal period.
影响因子：
2.9
作者：
GEORGE, HJ;MISRA, L;LEE, JC
通讯作者：
LEE, JC