Noninvasive Optical Monitoring of Cerebral Blood Flow and EEG Spectral Responses after Severe Traumatic Brain Injury: A Case Report.

Noninvasive Optical Monitoring of Cerebral Blood Flow and EEG Spectral Responses after Severe Traumatic Brain Injury: A Case Report.
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重型颅脑损伤后脑血流和脑电图谱反应的无创光学监测:1例报告。

DOI:
10.3390/brainsci11081093
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发表时间:
2021-08-20
期刊:
影响因子:
3.3
通讯作者:
Sunar U
Sunar U
中科院分区:
医学4区
文献类型:
--
作者:
Poon CS;Rinehart B;Langri DS;Rambo TM;Miller AJ;Foreman B;Sunar U

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严重脑损伤的幸存者可能需要在神经重症监护病房(神经 - ICU)接受护理,在那里大脑很容易遭受继发性脑损伤。因此,在神经 - ICU中需要无创的、床边的、连续的脑血流监测方法。我们的目标是通过脑电图(EEG)和功能性光谱技术(EEG - 光学)仪器及分析的联合测量来满足这一需求,以提供有关大脑活动和功能的数据的互补融合。我们利用漫射相关光谱法在神经 - ICU中对一名创伤性脑损伤患者的脑血流进行评估。本病例证明了连续记录无创性脑血流瞬变的可行性,这种瞬变与金标准的有创测量以及脑电图数据中的频率成分变化具有良好的相关性。
Survivors of severe brain injury may require care in a neurointensive care unit (neuro-ICU), where the brain is vulnerable to secondary brain injury. Thus, there is a need for noninvasive, bedside, continuous cerebral blood flow monitoring approaches in the neuro-ICU. Our goal is to address this need through combined measurements of EEG and functional optical spectroscopy (EEG-Optical) instrumentation and analysis to provide a complementary fusion of data about brain activity and function. We utilized the diffuse correlation spectroscopy method for assessing cerebral blood flow at the neuro-ICU in a patient with traumatic brain injury. The present case demonstrates the feasibility of continuous recording of noninvasive cerebral blood flow transients that correlated well with the gold-standard invasive measurements and with the frequency content changes in the EEG data.
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