Key Factors for Improving Rigor and Reproducibility: Guidelines, Peer Reviews, and Journal Technical Reviews.

To respond to the NIH's policy for rigor and reproducibility in preclinical research, many journals have implemented guidelines and checklists to guide authors in improving the rigor and reproducibility of their research. Transparency in developing detailed prospective experimental designs and providing raw data are essential premises of rigor and reproducibility. Standard peer reviews and journal-specific technical and statistical reviews are critical factors for enhancing rigor and reproducibility. This brief review also shares some experience from Arteriosclerosis, Thrombosis, and Vascular Biology, an American Heart Association journal, that has implemented several mechanisms to enhance rigor and reproducibility for preclinical research.

为了响应美国国立卫生研究院（NIH）关于临床前研究的严谨性和可重复性的政策，许多期刊已经实施了指南和清单，以指导作者提高其研究的严谨性和可重复性。制定详细的前瞻性实验设计并提供原始数据的透明度是严谨性和可重复性的重要前提。标准的同行评审以及针对特定期刊的技术和统计评审是提高严谨性和可重复性的关键因素。这篇简短的综述还分享了美国心脏协会期刊《动脉粥样硬化、血栓形成和血管生物学》的一些经验，该期刊已经实施了若干机制来提高临床前研究的严谨性和可重复性。