Virchow's Triad and the Role of Thrombosis in COVID-Related Stroke.
Virchow's Triad and the Role of Thrombosis in COVID-Related Stroke.
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DOI：
10.3389/fphys.2021.769254
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发表时间：
2021
影响因子：
4
通讯作者：
McCauley MD
中科院分区：
文献类型：
--
作者：
Gonzalez-Gonzalez FJ;Ziccardi MR;McCauley MD
2019 年 12 月，严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）被确定为一种病毒传播疾病。三个月后，SARS-CoV-2 成为近年来最严重的流行病之一，在全球造成超过 2.35 亿病例，迄今为止造成至少 480 万人死亡。 SARS-COV-2感染最初被归类为呼吸道感染，但后来被认为是一种损害胃肠道、血液、心脏和神经系统的多系统疾病。通过这篇综述，我们的目的是描述感染 COVID-19 的患者脑血管事件的流行病学、危险因素、机制和治疗。在感染了 COVID-19 的患者中，与血栓栓塞性脑血管事件相关的神经系统表现很常见，并且在大多数情况下与不良预后相关。有必要更好地了解血栓形成机制和这种新疾病过程的病因学，以确定如何预防和治疗患者，以减少患者的住院时间、发病率和死亡率。
In December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified as a virally transmitted disease. Three months later, SARS-CoV-2 became one of the largest pandemics in recent times, causing more than 235 million cases globally, and accounting for at least 4.8 million deaths to date. SARS-COV-2 infection was initially classified as a respiratory tract infection, but later was recognized as a multisystemic disease compromising gastrointestinal, hematological, cardiac, and neurological systems. With this Review, we aim to describe the epidemiology, risk factors, mechanisms, and management of cerebrovascular events in patients infected with COVID-19. Neurological manifestations related to thromboembolic cerebrovascular events in patients infected with COVID-19 have been frequent and associated with poor prognosis in the majority of cases. A better understanding of the mechanisms of thrombosis and etiologies of this new disease process are necessary to determine how to prevent and treat patients to reduce their length of stay, morbidity, and mortality.
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影响因子：
8.3
作者：
Escalard, Simon;Maier, Benjamin;Piotin, Michel
通讯作者：
Piotin, Michel
影响因子：
8.3
作者：
Bekelis K;Missios S;Ahmad J;Labropoulos N;Schirmer CM;Calnan DR;Skinner J;MacKenzie TA
通讯作者：
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影响因子：
7.5
作者：
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通讯作者：
Endeman, H.
DOI：
10.1016/s2665-9913(20)30420-3
发表时间：
2021-03
期刊：
The Lancet. Rheumatology
影响因子：
--
作者：
McGonagle D;Bridgewood C;Ramanan AV;Meaney JFM;Watad A
通讯作者：
Watad A
影响因子：
9.1
作者：
Liu, Yingxia;Yang, Yang;Liu, Lei
通讯作者：
Liu, Lei