Understanding Long-Term Outcomes Following Sepsis: Implications and Challenges.
Understanding Long-Term Outcomes Following Sepsis: Implications and Challenges.
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DOI：
10.1007/s11908-016-0544-7
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发表时间：
2016-11
影响因子：
3.1
通讯作者：
Rubenfeld, Gordon D.
中科院分区：
文献类型：
--
作者：
Shankar-Hari, Manu;Rubenfeld, Gordon D.
Sepsis is life-threating organ dysfunction due to infection. Incidence of sepsis is increasing and the short-term mortality is improving, generating more sepsis survivors. These sepsis survivors suffer from additional morbidities such as higher risk of readmissions, cardiovascular disease, cognitive impairment and of death, for years following index sepsis episode. In the first year following index sepsis episode, approximately 60 % of sepsis survivors have at least one rehospitalisation episode, which is most often due to infection and one in six sepsis survivors die. Sepsis survivors also have a higher risk of cognitive impairment and cardiovascular disease contributing to the reduced life expectancy seen in this population, when assessed with life table comparisons. For optimal design of interventional trials to reduce these bad outcomes in sepsis survivors, in-depth understanding of major risk factors for these morbid events, their modifiability and a causal relationship to the pathobiology of sepsis is essential. This review highlights the recent advances, clinical and methodological challenges in our understanding of these morbid events in sepsis survivors.
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影响因子：
8.8
作者：
Esper, Annette M.;Moss, Marc;Martin, Greg S.
通讯作者：
Martin, Greg S.
del妄作为重症疾病幸存者长期认知障碍的预测指标。
影响因子：
8.8
作者：
Girard TD;Jackson JC;Pandharipande PP;Pun BT;Thompson JL;Shintani AK;Gordon SM;Canonico AE;Dittus RS;Bernard GR;Ely EW
通讯作者：
Ely EW
DOI：
10.1186/s13054-015-1068-5
发表时间：
2015-10-15
期刊：
Critical care (London, England)
影响因子：
--
作者：
Bataille A;Galichon P;Ziliotis MJ;Sadia I;Hertig A
通讯作者：
Hertig A
影响因子：
120.7
作者：
Boomer, Jonathan S.;To, Kathleen;Chang, Kathy C.;Takasu, Osamu;Osborne, Dale F.;Walton, Andrew H.;Bricker, Traci L.;Jarman, Stephen D., II;Kreisel, Daniel;Krupnick, Alexander S.;Srivastava, Anil;Swanson, Paul E.;Green, Jonathan M.;Hotchkiss, Richard S.
通讯作者：
Hotchkiss, Richard S.
影响因子：
5.7
作者：
Chavan, Sangeeta S.;Huerta, Patricio T.;Diamond, Betty
通讯作者：
Diamond, Betty