Natural products as molecular messengers.

Natural products as molecular messengers.
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DOI:
10.1021/np100754j
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发表时间:
2011-03-25
影响因子:
5.1
通讯作者:
Meinwald J
Meinwald J
中科院分区:
生物学2区
文献类型:
--
作者:
Meinwald J

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天然化合物的化学研究长期以来一直在寻找药物、染料、杀虫剂、香料和芳香剂。此外,将生命本身理解为一种化学现象的更深层次的目标激励了一代又一代的科学家。这些研究的一个结果是认识到天然产物通常作为生物信号传导剂发挥核心作用。我们认为天然产物的角度来看,生产和/或响应他们的生物体,并建议如何天然存在的化合物可能会获得其化学通讯的作用。
The chemistry of naturally-occurring compounds has long been pursued in the search for medicines, dyes, pesticides, flavors, and fragrances. In addition, the deeper aim of understanding life itself as a chemical phenomenon has motivated generations of scientists. One consequence of such studies has been the realization that natural products often serve central roles as biological signaling agents. We consider natural products from the viewpoint of the organisms that produce and/or respond to them, and suggest how a naturally-occurring compound may acquire its role in chemical communication.
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