Lung transplant waitlist outcomes in the United States and patient travel distance.

Lung transplant waitlist outcomes in the United States and patient travel distance.
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DOI:
10.1111/ajt.16193
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发表时间:
2021-01
期刊:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
影响因子:
--
通讯作者:
Schold JD
Schold JD
中科院分区:
其他
文献类型:
--
作者:
Tsuang WM;Arrigain S;Lopez R;Budev M;Schold JD

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在美国,到达肺移植医院的患者旅行距离范围很广。尚不清楚患者旅行距离是否与等待名单结果相关。我们对2006年1月1日至2017年5月31日期间使用移植受者科学登记的患者进行了队列研究。使用SAS URL访问Google地图测量从患者的永久邮政编码到移植医院的旅行距离,并使用多变量竞争风险回归模型进行评估。有22,958例患者符合入选标准。平均行驶距离为69.7英里。在旅行超过60英里的患者中,41.2%的人绕过了较近的医院,并在较远的医院寻求上市。在调整后的模型中,与旅行≤60英里的患者相比,旅行>360英里的患者的等待名单移除的亚危险比(SHR)低27(SHR 0.73,95% CI:0.60,0.89,p =0.002),等待名单死亡的亚危险降低16%(SHR 0.84; 95%CI 0.73-0.95,p =0.07),移植可能性增加13%(SHR 1.13,95%CI:1.07,1.20,p <0.001)。许多患者绕过最近的移植医院,较长的患者旅行距离与有利的等待结果相关。
There is a broad range of patient travel distances to reach a lung transplant hospital in the United States. Whether patient travel distance is associated with waitlist outcomes is unknown. We present a cohort study of patients listed between January 1, 2006 and May 31, 2017 using the Scientific Registry of Transplant Recipients. Travel distance was measured from the patient’s permanent zip code to the transplant hospital using SAS URL access to Google Maps, and assessed using multivariable competing risk regression models. There were 22,958 patients who met inclusion criteria. Median travel distance was 69.7 miles. Among patients who traveled >60 miles, 41.2% bypassed a closer hospital and sought listing at a more distant hospital. In the adjusted models, when compared to patients who traveled ≤60 miles, patients who traveled >360 miles had a 27% lower subhazard ratio (SHR) for waitlist removal (SHR 0.73, 95% CI: 0.60, 0.89, p =0.002), 16% lower subhazard for waitlist death (SHR 0.84; 95% CI 0.73–0.95, p =0.07), and 13% increased likelihood for transplant (SHR 1.13, 95% CI: 1.07, 1.20, p <0.001). Many patients bypassed the nearest transplant hospital, and longer patient travel distance was associated with favorable waitlist outcomes.
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