Wastewater-based detection of an influenza outbreak
Wastewater-based detection of an influenza outbreak
复制标题
基于废水的流感爆发检测
DOI：
10.1101/2022.02.15.22271027
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发表时间：
2022
期刊：
影响因子：
--
通讯作者：
K. Wigginton
中科院分区：
文献类型：
--
作者：
M. Wolfe;D. Duong;K. Bakker;M. Ammerman;L. Mortenson;B. Hughes;E. Martin;B. J. White;A. Boehm;K. Wigginton
传统的流感监测为控制战略提供了信息，但可能落后于疫情爆发和病例数不足，而废水监测对于监测疫情的近实时动态是有效的，但尚未尝试用于流感。我们在一次活跃的疫情期间定量了废水中的甲型流感病毒RNA。RNA浓度与报告的临床病例密切相关，反映了疫情的模式和规模，表明这种方法有助于早期发现。
Traditional influenza surveillance informs control strategies but can lag behind outbreak onset and undercount cases, while wastewater surveillance is effective for monitoring near real-time dynamics of outbreaks but has not been attempted for influenza. We quantified Influenza A virus RNA in wastewater during an active outbreak. RNA concentrations were strongly associated with reported clinical cases and reflected the outbreak pattern and magnitude, suggesting this approach could aid in early detection.
DOI：
10.1056/nejmp1307752
发表时间：
2013-08-01
期刊：
The New England journal of medicine
影响因子：
--
作者：
Salathé M;Freifeld CC;Mekaru SR;Tomasulo AF;Brownstein JS
通讯作者：
Brownstein JS
影响因子：
12.8
作者：
Symonds EM;Nguyen KH;Harwood VJ;Breitbart M
通讯作者：
Breitbart M