Optofluidic particle concentration by a long-range dual-beam trap.
Optofluidic particle concentration by a long-range dual-beam trap.
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DOI:
10.1364/ol.34.002306
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发表时间:
2009-08-01
期刊:
影响因子:
3.6
通讯作者:
Schmidt H
中科院分区:
文献类型:
--
作者:
Kühn S;Lunt EJ;Phillips BS;Hawkins AR;Schmidt H
Ultrahigh sensitivity detection of particles in solution implies the ability to detect at very low concentrations. At the single-particle level, this is achieved through fluorescence detection, reaching down to single fluorophores. Sensitivity may also be improved by concentrating many particles into a compact cluster, thus “integrating” the signal of many particles. We show how both ways can be combined on an optofluidic chip in a fully planar geometry utilizing counterpropagating liquid-core waveguide modes to form a loss-based optical trap. This all-optical concentrator can increase the concentration of particles by more than 2 orders of magnitude and also provides a convenient, nondispersive means of transport for particle ensembles.
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