Prevalence and awareness of CKD among African Americans: the Jackson Heart Study.
Prevalence and awareness of CKD among African Americans: the Jackson Heart Study.
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DOI：
10.1053/j.ajkd.2008.08.035
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发表时间：
2009-02
期刊：
影响因子：
--
通讯作者：
Crook E
中科院分区：
文献类型：
--
作者：
Flessner MF;Wyatt SB;Akylbekova EL;Coady S;Fulop T;Lee F;Taylor HA;Crook E
慢性肾脏疾病（CKD）导致终末期肾脏疾病（ESRD），并在世界范围内日益流行。在美国，非裔美国人的ESRD发病率是白人的四倍。Jackson心脏研究（JHS）的观察队列将CKD定义为肾小球滤过率< 60 ml/min/1.73 m2，存在蛋白尿或正在进行透析。在基线访问时获得JHS参与者的病史，包括疾病意识和药物治疗、人体测量、血清和尿液样本。利用logistic回归模型评估CKD患病率和认知与选定的人口统计学、社会经济、医疗保健可及性和疾病状态参数之间的关系。JHS患者CKD患病率为20%；CKD知知率仅为15.8%。年龄较大的参与者患病率较高，但也更了解CKD。高血压、糖尿病、心血管疾病（CVD）、高胆固醇血症、高甘油三酯血症、年龄和腰围增加以及单身或少运动与CKD有关。只有CKD分期的进展与认知相关。JHS人群对CKD的患病率较高，但知晓率较低，尤其是病情较轻的人群。这强调了早期诊断和加强对保健提供者和一般人群的教育的必要性。
Chronic kidney disease (CKD) leads to End Stage Renal Disease (ESRD) and is a growing epidemic throughout the world. In the United States, African Americans have an incidence of ESRD four times that of Whites. Cross Sectional to examine the prevalence and awareness of CKD in African Americans Observational Cohort in the Jackson Heart Study (JHS) CKD was defined as estimated glomerular filtration rate < 60 ml/min/1.73 m2, presence of albuminuria, or being on dialysis Data from the Jackson Heart Study (JHS) were analyzed. Medical history including disease awareness and drug therapy, anthropometric measurements, serum, and urine samples were obtained from JHS participants at the baseline visit. Associations between CKD prevalence and awareness and selected demographic, socioeconomic, healthcare access, and disease status parameters were assessed utilizing logistic regression models. The prevalence of CKD in the JHS was 20%; CKD awareness was only 15.8%. Older participants had higher prevalence but were also more aware of CKD. Hypertension, diabetes, cardiovascular disease (CVD), hypercholesterolemia, hypertriglyceridemia, increasing age and waist circumference as well as being single or less physically active were associated with CKD. Only advancing of CKD stage was associated with awareness. Cross-sectional assessment, single urine measurement The JHS has a high prevalence and low awareness of CKD, especially those with less severe disease status. This emphasizes the need for earlier diagnosis and increased education of health care providers and the general population.
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影响因子：
13.6
作者：
Perkins, Bruce A.;Ficociello, Linda H.;Krolewski, Andrzej S.
通讯作者：
Krolewski, Andrzej S.
DOI：
10.2215/cjn.03390807
发表时间：
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影响因子：
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作者：
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作者：
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通讯作者：
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影响因子：
13.6
作者：
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通讯作者：
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