Reduced progression to type 2 diabetes from impaired glucose tolerance after a 2-day in-hospital diabetes educational program: the Joetsu Diabetes Prevention Trial.
Reduced progression to type 2 diabetes from impaired glucose tolerance after a 2-day in-hospital diabetes educational program: the Joetsu Diabetes Prevention Trial.
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DOI：
10.2337/dc07-2272
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发表时间：
2008-10
期刊：
影响因子：
16.2
通讯作者：
Tanaka Y
中科院分区：
文献类型：
--
作者：
Kawahara T;Takahashi K;Inazu T;Arao T;Kawahara C;Tabata T;Moriyama H;Okada Y;Morita E;Tanaka Y
目的：我们评估了为期两天的住院糖尿病教育计划在预防或延缓糖耐量受损(IGT)进展为2型糖尿病方面的效果，包括分析计划后血脂、体重和血压的变化。研究设计与方法：426例初诊IGT患者，年龄(51±9)岁，体重指数(BMI)24.6±3.9 kg/m2，随机分为3组，其中短期住院加糖尿病教育支持组143例，非住院糖尿病教育支持组141例，非住院糖尿病教育支持组142例。结果：平均随访3.1年。STH组、DES组和对照组的糖尿病发病率分别为每100人年8.0、10.7和13.2例。与对照组相比，STH组糖尿病发病率降低42%(95%可信区间33~51%)，DES组糖尿病发病率降低27%(15~37%)。STH组的糖尿病发病率比DES组低21%(10-31%)。结论：每3个月进行为期2天的糖尿病教育和支持的住院计划在预防或延缓从IGT到糖尿病的进展方面比仅每3个月进行一次糖尿病教育和支持更有效。
OBJECTIVE—We assessed the effects of a 2-day in-hospital diabetes educational program in preventing or delaying progression of impaired glucose tolerance (IGT) to type 2 diabetes, including analysis of changes in serum lipids, body weight, and blood pressure after the program. RESEARCH DESIGN AND METHODS—A total of 426 subjects (51 ± 9 years, BMI 24.6 ± 3.9 kg/m2) with newly diagnosed IGT were randomly assigned to three groups, 143 as the short-term hospitalization with diabetes education and support (STH) group, 141 as the nonhospitalization but diabetes education and support (DES) group, and 142 as the neither hospitalization nor education (control) group. RESULTS—The average follow-up was 3.1 years. The incidence of diabetes was 8.0, 10.7, and 13.2 cases per 100 person-years for STH, DES, and control groups, respectively. The incidence of diabetes was 42% lower (95% CI 33–51%) in the STH group and 27% lower (15–37%) in the DES group than in the control group. The incidence of diabetes was 21% lower (10–31%) in the STH group than in the DES group. CONCLUSIONS—The 2-day in-hospital program with diabetes education and support every 3 months was more effective in preventing or delaying the progression from IGT to diabetes than only diabetes education and support every 3 months.
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影响因子：
158.5
作者：
Knowler, WC;Barrett-Connor, E;Nathan, DM
通讯作者：
Nathan, DM
影响因子：
8.2
作者：
KADOWAKI, T;MIYAKE, Y;KOSAKA, K
通讯作者：
KOSAKA, K
影响因子：
8.2
作者：
ERIKSSON, KF;LINDGARDE, F
通讯作者：
LINDGARDE, F
影响因子：
16.2
作者：
Pan, XR;Li, GW;Howard, BV
通讯作者：
Howard, BV
影响因子：
5.1
作者：
Chen, HD;Shaw, CK;Lee, ML
通讯作者：
Lee, ML