[The study of biological monitoring of inorganic arsenic exposure].
[The study of biological monitoring of inorganic arsenic exposure].
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无机砷暴露生物监测研究[J].
DOI：
10.1265/jjh.49.973
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发表时间：
1995
期刊：
影响因子：
--
通讯作者：
H. Yamauchi
中科院分区：
文献类型：
--
作者：
H. Yamauchi
本综述将描述无机砷暴露的生物监测方法，该方法描述了尿液中测量的砷的化学形态。这些研究建立了一种对无机砷暴露进行与暴露水平相关的生物监测的方法。低水平暴露只能通过测定尿无机砷浓度来监测。高水平暴露明显导致尿无机砷增加，可测定甲基化砷（MA）、二甲基化砷（DMA）以及尿无机砷及其代谢物（无机砷+MA+DMA）的总和。尿砷甜菜碱被证明是专门来自海鲜的砷，可以与职业砷暴露区分开来。如今，半导体行业越来越多地使用砷化镓和砷化铟。半导体工厂很难进行环境空气中砷的测定。通过测定头发中的砷来监测砷暴露似乎仅在用于砷的环境监测而不是生物监测时才有价值。
This review will describe method for biological monitoring of inorganic arsenic exposure, that delineates the chemical species of arsenic measured in urine. The studies established a method for exposure-level-dependent biological monitoring of inorganic arsenic exposure. Low-level exposure could be monitored only by determining the urinary inorganic arsenic concentration. High-level exposures clearly produced increased urinary inorganic arsenic, methylated arsenic (MA), dimethylated arsenic (DMA) and the sum of urinary inorganic arsenic and its metabolites (inorganic arsenic+MA+DMA) could be determined. Urinary arsenobetaine proved to be specifically seafood-derived arsenic, which could be distinguished from occupational arsenic exposure. There is increased use of gallium arsenide and indium arsenide in the semiconductor industry today. The determination of arsenic in ambient air is difficult to carry out in semiconductor factories. Monitoring arsenic exposure by determining the arsenic in the hair appeared to be of value only when used for environmental monitoring of arsenic rather than for biological monitoring.
影响因子：
3.8
作者：
Yamauchi,H;Takahashi,K;Yamamura,Y;Fowler,BA
通讯作者：
Fowler,BA
砷化镓的体外溶解度和体内毒性。
影响因子：
3.8
作者：
Webb,DR;Sipes,IG;Carter,DE
通讯作者：
Carter,DE