Analysis and Synthesis of Cochlear Mechanical Function Using Models
Analysis and Synthesis of Cochlear Mechanical Function Using Models
复制标题
使用模型分析和综合耳蜗机械功能
DOI：
10.1007/978-1-4612-4070-9_3
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发表时间：
1996
期刊：
影响因子：
--
通讯作者：
D. Mountain
中科院分区：
文献类型：
--
作者：
A. Hubbard;D. Mountain
本章首先简要回顾耳蜗解剖学和生理学（另见 Echteler、Fay 和 Popper 1994），然后逐步介绍耳蜗建模。我们将解剖学和生理学与模型联系起来，从而扩大了潜在感兴趣的读者群。大多数最先进的耳蜗模型都包括外毛细胞的实施例，这些外毛细胞已被证明会响应跨膜电压而改变长度。据推测，这种电动性是机械放大过程的基础，该过程使哺乳动物检测微弱声音的能力提高了一百倍。本卷的第 4 章（Mountain 和 Hubbard）进一步考虑了毛细胞运动的生物物理学，而在本章中，毛细胞响应其自身静纤毛运动提供反馈力的能力被认为是哺乳动物听力最敏感方面的引擎。这项工作并不详尽，而是试图详细介绍那些具有重大历史意义或代表耳蜗建模当前技术水平的模型。我们试图为读者解释数据和模型的当前意义。
This chapter begins with a brief review of cochlear anatomy and physiology (see also Echteler, Fay, and Popper 1994), and then progresses through the modeling of the cochlea. We relate anatomy and physiology to models, thus broadening the base of potentially interested readers. Most state-of-the-art cochlear models include an embodiment of outer hair cells that have been shown to change length in response to transmembrane voltage. This electromotility is hypothesized to underlie a process of mechanical amplification that increases the ability of mammals to detect faint sounds by a hundredfold. Chapter 4 (Mountain and Hubbard) of this volume further considers the biophysics of hair cell motility, while in this chapter, the ability of hair cells to provide a feedback force in response to the motion of their own stereocilia is considered to be the engine that underlies the most sensitive aspects of mammalian hearing. This work is not exhaustive, but instead attempts to cover in some detail those models that are either of significant historical interest or represent the current state of the art in cochlear modeling. We attempt to interpret the current significance of both data and models for the reader.
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影响因子：
2.4
作者：
NEELY, ST;KIM, DO
通讯作者：
KIM, DO
影响因子：
2.4
作者：
OLSON, ES;MOUNTAIN, DC
通讯作者：
MOUNTAIN, DC
豚鼠内毛细胞和基底膜反应的双音抑制。
DOI：
10.1121/1.405619
发表时间：
1993
期刊：
The Journal of the Acoustical Society of America
影响因子：
--
作者：
Nuttall,AL;Dolan,DF
通讯作者：
Dolan,DF
内淋巴电位的变化和交叉橄榄耳蜗束刺激改变了耳蜗力学。
DOI：
10.1126/science.7414321
发表时间：
1980
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Mountain,DC
通讯作者：
Mountain,DC