Posterior polymorphous dystrophy of the cornea

Posterior polymorphous dystrophy of the cornea
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角膜后部多形性营养不良

DOI:
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发表时间:
2005
期刊:
Graefe's Archive for Clinical and Experimental Ophthalmology
影响因子:
--
通讯作者:
P. Vinciguerra
P. Vinciguerra
中科院分区:
--
文献类型:
--
作者:
G. P. Felice;P. Braidotti;G. Viale;F. Bergamini;P. Vinciguerra

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A corneal button excised from a 2-month-old infant with congenital posterior polymorphous dystrophy of the cornea, a rare disease affecting Descemet's membrane and endothelium, was examined by electron microscopy. We observed irregularly arranged, sometimes multilayered cells with marked epithelial features, lining the posterior surface of the cornea in place of the endothelium, and Descemet's membrane with focal alterations sometimes involving all of its layers. We interpreted these abnormal cells as epithelial-like cells. As these findings were in a very young patient, which is unusual, we concluded that the onset of the disease may take place in the early period of intrauterine life, corresponding to the beginning of Descemet's membrane production.
DOI: --
发表时间: 1984-03
影响因子: 4.4
作者:
C. Murphy;J. Alvarado;Richard Jusrer;M. Maglio
通讯作者: C. Murphy;J. Alvarado;Richard Jusrer;M. Maglio