Aryl Methyl Ketones: Versatile Synthons in the Synthesis of Heterocyclic Compounds.

Aryl Methyl Ketones: Versatile Synthons in the Synthesis of Heterocyclic Compounds.
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DOI:
10.1055/a-1826-2852
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发表时间:
2022-06
期刊:
SynOpen (2017)
影响因子:
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通讯作者:
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其他
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芳香杂环化合物的合成由于在药物分子、天然产物和其它具有生物学意义的化合物中大量存在而引起了人们的广泛关注。因此,需要使用容易获得的起始材料的直接合成方案。在过去的十年中,杂环化合物的合成有了很大的发展,特别是在金属催化和碘辅助的方法。这个图形审查的重点是显着的反应,从过去的十年中使用芳基和杂芳基甲基酮为起始材料,包括代表性的反应机理。
The synthesis of aromatic heterocycles has attracted substantial attention due to the abundance of these heterocycles in drug molecules, natural products, and other compounds of biological interest. Accordingly, there is a demand for straightforward synthetic protocols toward such compounds using readily available starting materials. In the past decade, there have been substantial developments in heterocycle synthesis, especially in metal-catalyzed and iodine-assisted approaches. This graphical review focuses on notable reactions from the past decade using aryl and heteroaryl methyl ketones as starting materials, including representative reaction mechanisms.
DOI: 10.1021/acsomega.1c01466
发表时间: 2021-06-08
期刊: ACS omega
影响因子: 4.1
作者:
Marpna ID;Shangpliang OR;Wanniang K;Kshiar B;Lipon TM;Laloo BM;Myrboh B
通讯作者: Myrboh B