Characterization of tree allergy prevalence in children younger than 4 years.
Characterization of tree allergy prevalence in children younger than 4 years.
复制标题
4 岁以下儿童树木过敏患病率的特征。
DOI：
10.1016/j.anai.2014.01.014
复制
发表时间：
2014
期刊：
影响因子：
--
通讯作者：
Phipatanakul,Wanda
中科院分区：
文献类型：
--
作者：
Sedaghat,AhmadR;Sheehan,WilliamJ;Bharmanee,Apinya;Harris,Kendra;Phipatanakul,Wanda
儿童特应性疾病的患病率和严重程度正在增加。1，2对这些疾病的影响是多方面的。在幼儿中，空气过敏原敏感性的存在可能是持续性哮喘发展的危险因素。3伴随的吸入性过敏原敏感性经常出现在慢性上呼吸道疾病4和下呼吸道疾病5中，并且还与儿童鼻炎和哮喘的严重程度相关。因此，通过测试了解特应性儿童的空气过敏原敏感性特征不仅对于制定治疗避免措施很重要，而且作为预后指标也很重要。7由于致敏需要长时间暴露，一些临床医生建议暂停对婴儿或幼儿进行正式的空气过敏原敏感性测试，特别是对户外过敏原的测试。我们之前描述了所有年龄的特应性儿童的空气过敏原敏感性特征，并注意到，尽管室内空气过敏原敏感性更常见，但对室外空气过敏原（树木、草地或杂草花粉）的致敏性存在于9.5%的0至2岁儿童中，18.2%的2至4岁儿童对花粉致敏。特别是，树花粉是这些年幼儿童的主要致敏物，患病率接近尘螨致敏。8
The prevalence and severity of atopic diseases in children are increasing. 1, 2 The effects of aeroallergen sensitivity on these diseases are manifold. In young children, the presence of aero-allergen sensitivity may serve as a risk factor for the development of persistent asthma. 3 Concomitant aeroallergen sensitivity is frequently present in both chronic upper4 and lower airway diseases5 and is additionally associated with severity of rhinitis and asthma in children. 5, 6 Therefore, understanding of an atopic child’s aeroallergen sensitivity profile through testing is important not only for instituting therapeutic avoidance measures but also as a prognostic indicator. 7Because sensitization requires exposure over time, some clinicians suggest withholding formal testing for aeroallergen sensitivity, in particular to outdoor allergens, in infants or young children. We previously described the aeroallergen sensitivity profiles of atopic children of all ages8 and noted that, although indoor aeroallergen sensitivity was more common, sensitization to outdoor aeroallergens (tree, grass, or weed pollens) was present in 9.5% of children aged 0 to 2 years and 18.2% of children aged 2 to 4 years being sensitized to pollens. In particular, tree pollen was the primary sensitizer in these younger children, with prevalence rates approaching that of dust mite sensitization. 8
人绒毛膜滋养层体外肾素释放：环 Amp 和蛋白激酶 C 的作用
DOI：
--
发表时间：
1987
期刊：
影响因子：
--
作者：
A. Poisner;P. Agrawal;R. Poisner
通讯作者：
R. Poisner