Association of current and former smoking with body mass index: A study of smoking discordant twin pairs from 21 twin cohorts.
Association of current and former smoking with body mass index: A study of smoking discordant twin pairs from 21 twin cohorts.
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DOI：
10.1371/journal.pone.0200140
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发表时间：
2018
期刊：
影响因子：
3.7
通讯作者：
Silventoinen K
中科院分区：
文献类型：
--
作者：
Piirtola M;Jelenkovic A;Latvala A;Sund R;Honda C;Inui F;Watanabe M;Tomizawa R;Iwatani Y;Ordoñana JR;Sánchez-Romera JF;Colodro-Conde L;Tarnoki AD;Tarnoki DL;Martin NG;Montgomery GW;Medland SE;Rasmussen F;Tynelius P;Tan Q;Zhang D;Pang Z;Rebato E;Stazi MA;Fagnani C;Brescianini S;Busjahn A;Harris JR;Brandt I;Nilsen TS;Cutler TL;Hopper JL;Corley RP;Huibregtse BM;Sung J;Kim J;Lee J;Lee S;Gatz M;Butler DA;Franz CE;Kremen WS;Lyons MJ;Magnusson PKE;Pedersen NL;Dahl Aslan AK;Öncel SY;Aliev F;Derom CA;Vlietinck RF;Loos RJF;Silberg JL;Maes HH;Boomsma DI;Sørensen TIA;Korhonen T;Kaprio J;Silventoinen K
吸烟者的体重往往比从不吸烟者轻，而成功戒烟会导致体重增加。由于吸烟者和非吸烟者在遗传和环境家庭背景上可能存在差异，我们分析了来自双胞胎的数据，其中双胞胎的吸烟行为不同，以评估在控制家庭背景后，吸烟与体重指数（BMI）之间的关联是否仍然存在。国际CODATwins数据库包括1960年至2012年间测量的156593名18-69岁双胞胎的吸烟和体重指数信息。基于个体的数据（230,378个测量值）和吸烟不一致双胞胎的数据（共30014个成对测量值，36%来自同卵[MZ]对）采用线性固定效应回归模型，以10年为周期进行分析。在MZ对中，吸烟的同卵双胞胎男性的BMI平均比不吸烟的同卵双胞胎低0.57 kg/m2(95%可信区间（CI）： 0.49, 0.70)，女性的BMI平均比不吸烟的同卵双胞胎低0.65 kg/m2 （95% CI: 0.52, 0.79）。与目前吸烟的MZ同卵双胞胎相比，曾经吸烟的男性BMI指数高出0.70 kg/m2 (95% CI: 0.63, 0.78)，女性BMI指数高出0.62 kg/m2 （95% CI: 0.51, 0.73）。将曾经吸烟的同卵双胞胎与从不吸烟的同卵双胞胎进行比较，BMI差异不大（男性为0.13 kg/m2, 95% CI 0.04, 0.23；女性为-0.04 kg/m2, 95% CI -0.16, 0.09）。这种关联在异卵对和作为个体分析的双胞胎中也是相似的。观察到的一系列横断面关联与性别、年龄和测量十年无关。吸烟与较低的身体质量指数有关，而戒烟与较高的身体质量指数有关。然而，吸烟和随后戒烟对体重发展的净影响似乎是最小的，即从不超过平均0.7公斤/平方米。
Smokers tend to weigh less than never smokers, while successful quitting leads to an increase in body weight. Because smokers and non-smokers may differ in genetic and environmental family background, we analysed data from twin pairs in which the co-twins differed by their smoking behaviour to evaluate if the association between smoking and body mass index (BMI) remains after controlling for family background. The international CODATwins database includes information on smoking and BMI measured between 1960 and 2012 from 156,593 twin individuals 18–69 years of age. Individual-based data (230,378 measurements) and data of smoking discordant twin pairs (altogether 30,014 pairwise measurements, 36% from monozygotic [MZ] pairs) were analysed with linear fixed-effects regression models by 10-year periods. In MZ pairs, the smoking co-twin had, on average, 0.57 kg/m2 lower BMI in men (95% confidence interval (CI): 0.49, 0.70) and 0.65 kg/m2 lower BMI in women (95% CI: 0.52, 0.79) than the never smoking co-twin. Former smokers had 0.70 kg/m2 higher BMI among men (95% CI: 0.63, 0.78) and 0.62 kg/m2 higher BMI among women (95% CI: 0.51, 0.73) than their currently smoking MZ co-twins. Little difference in BMI was observed when comparing former smoking co-twins with their never smoking MZ co-twins (0.13 kg/m2, 95% CI 0.04, 0.23 among men; -0.04 kg/m2, 95% CI -0.16, 0.09 among women). The associations were similar within dizygotic pairs and when analysing twins as individuals. The observed series of cross-sectional associations were independent of sex, age, and measurement decade. Smoking is associated with lower BMI and smoking cessation with higher BMI. However, the net effect of smoking and subsequent cessation on weight development appears to be minimal, i.e. never more than an average of 0.7 kg/m2.
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DOI：
10.1177/1745691610383511
发表时间：
2010-09
期刊：
Perspectives on psychological science : a journal of the Association for Psychological Science
影响因子：
--
作者：
McGue M;Osler M;Christensen K
通讯作者：
Christensen K
影响因子：
2.9
作者：
Morris RW;Taylor AE;Fluharty ME;Bjørngaard JH;Åsvold BO;Elvestad Gabrielsen M;Campbell A;Marioni R;Kumari M;Korhonen T;Männistö S;Marques-Vidal P;Kaakinen M;Cavadino A;Postmus I;Husemoen LL;Skaaby T;Ahluwalia TV;Treur JL;Willemsen G;Dale C;Wannamethee SG;Lahti J;Palotie A;Räikkönen K;McConnachie A;Padmanabhan S;Wong A;Dalgård C;Paternoster L;Ben-Shlomo Y;Tyrrell J;Horwood J;Fergusson DM;Kennedy MA;Nohr EA;Christiansen L;Kyvik KO;Kuh D;Watt G;Eriksson JG;Whincup PH;Vink JM;Boomsma DI;Davey Smith G;Lawlor D;Linneberg A;Ford I;Jukema JW;Power C;Hyppönen E;Jarvelin MR;Preisig M;Borodulin K;Kaprio J;Kivimaki M;Smith BH;Hayward C;Romundstad PR;Sørensen TI;Munafò MR;Sattar N
通讯作者：
Sattar N
影响因子：
7.7
作者：
Freathy RM;Kazeem GR;Morris RW;Johnson PC;Paternoster L;Ebrahim S;Hattersley AT;Hill A;Hingorani AD;Holst C;Jefferis BJ;Kring SI;Mooser V;Padmanabhan S;Preisig M;Ring SM;Sattar N;Upton MN;Vollenweider P;Waeber G;Sørensen TI;Frayling TM;Watt G;Lawlor DA;Whincup PH;Tozzi F;Davey Smith G;Munafò M
通讯作者：
Munafò M
DOI：
10.1016/j.jaac.2011.09.007
发表时间：
2011-12-01
影响因子：
13.3
作者：
Groen-Blokhuis, Maria M.;Middeldorp, Christel M.;Boomsma, Dorret I.
通讯作者：
Boomsma, Dorret I.
影响因子：
16.6
作者：
Justice, Anne E.;Winkler, Thomas W.;Cupples, L. Adrienne
通讯作者：
Cupples, L. Adrienne