The effects of tooth extraction on alveolar bone biomechanics in the miniature pig, Sus scrofa.
The effects of tooth extraction on alveolar bone biomechanics in the miniature pig, Sus scrofa.
复制标题
DOI：
10.1016/j.archoralbio.2010.05.014
复制
发表时间：
2010-09
影响因子：
3
通讯作者：
Egbert, M.
中科院分区：
文献类型：
--
作者：
Yeh, K.;Popowics, T.;Rafferty, K.;Herring, S.;Egbert, M.
本研究探讨了咬合在小型猪（Sus scrofa）牙槽骨生物力学特性发育中的作用。所检验的假设是，支持咬合牙的组织相较于非咬合牙的组织会表现出更大的刚度和更小的应变。
在一侧拔除与正在萌出的下颌第一磨牙（M1）相对的上颌牙。对侧形成咬合。连续给予的荧光色素标记追踪骨矿化沉积率（MAR）。一项终结性实验测量了咀嚼过程中咬合侧和非咬合侧的体内颊侧牙槽骨应变。随后使用材料试验机（MTS/Sintech）测量咬合加载过程中的离体牙槽应变。计算了整个标本的刚度和主应变。
在咬合期间，拔除侧的MAR往往较高。体内颊侧剪切应变在咬合侧牙槽骨中高于拔除侧（分别平均为471με和281με；p = 0.04）；然而，离体剪切应变在两侧之间无显著差异。拔除侧和咬合侧标本的刚度不同，在低载荷范围差异显著（分别为344 MPa和668 MPa；p = 0.04）。
体内更大的剪切应变可能表明咬合侧咀嚼更有力，而离体骨应变大小的相似性表明，无论咬合状态如何，牙槽骨结构和咬合载荷传递具有相似性。观察到的标本刚度的巨大总体变化可能归因于牙周韧带的差异，而非牙槽骨。
This study investigated the role of occlusion in the development of biomechanical properties of alveolar bone in the miniature pig, Sus scrofa. The hypothesis tested was that the tissues supporting an occluding tooth would show greater stiffness and less strain than that of a non-occluding tooth. Maxillary teeth opposing the erupting lower first molar (M1) were extracted on one side. Occlusion developed on the contralateral side. Serially administered fluorochrome labels tracked bone mineralization apposition rate (MAR). A terminal experiment measured in vivo buccal alveolar bone strain on occluding and non-occluding sides during mastication. Ex vivo alveolar strains during occlusal loading were subsequently measured using a materials testing machine (MTS/Sintech). Whole specimen stiffness and principal strains were calculated. MAR tended to be higher on the extraction side during occlusion. In vivo buccal shear strains were higher in the alveolar bone of the occluding side vs. the extraction side (mean of 471με vs. 281με, respectively; p=0.04); however, ex vivo shear strains showed no significant differences between sides. Stiffness differed between extraction and occlusion side specimens, significantly so in the low load range (344 vs. 668MPa, respectively; p=0.04). Greater in vivo shear strains may indicate more forceful chews on the occluding side, whereas the similarity in ex vivo bone strain magnitude suggests a similarity in alveolar bone structure and occlusal load transmission regardless of occlusal status. The big overall change in specimen stiffness that was observed was likely attributable to differences in the periodontal ligament rather than alveolar bone.
登录
查看更多内容
影响因子：
1.5
作者：
HYLANDER, WL
通讯作者：
HYLANDER, WL
影响因子：
2.8
作者：
HYLANDER, WL;JOHNSON, KR;CROMPTON, AW
通讯作者：
CROMPTON, AW
DOI：
10.1016/j.ijom.2006.01.023
发表时间：
2006-07-01
影响因子：
2.4
作者：
Bousdras, V. A.;Cunningham, J. L.;Goodship, A. E.
通讯作者：
Goodship, A. E.
影响因子：
3
作者：
WEIJS, WA;JONGH, HJD
通讯作者：
JONGH, HJD
影响因子：
1.5
作者：
Rafferty, KL;Herring, SW;Marshall, CD
通讯作者：
Marshall, CD