Assessing a norming intervention to promote acceptance of HIV testing and reduce stigma during household tuberculosis contact investigation: protocol for a cluster-randomised trial.
Assessing a norming intervention to promote acceptance of HIV testing and reduce stigma during household tuberculosis contact investigation: protocol for a cluster-randomised trial.
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DOI：
10.1136/bmjopen-2022-061508
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发表时间：
2022-05-25
期刊：
影响因子：
2.9
通讯作者：
Katamba, Achilles
中科院分区：
文献类型：
--
作者：
Armstrong-Hough, Mari;Ggita, Joseph;Gupta, Amanda J.;Shelby, Tyler;Nangendo, Joanita;Ayen, Daniel Okello;Davis, J. L.;Katamba, Achilles
对于结核病 (TB) 患者的家庭接触者来说，了解艾滋病毒状况非常重要。结核病接触者调查期间的家庭艾滋病毒检测可提高艾滋病毒状况的认识。家访期间的社交互动可能会影响人们对艾滋病毒检测的耻辱感和接受程度。我们设计了一项干预措施，以规范和促进家庭艾滋病毒检测的采用，包括五个组成部分：指导选择第一位检测人员；亲社会邀请脚本；选择退出框架；可选择共享要测试的决策；并掩盖不进行测试的决定。我们将在家庭随机对照试验中评估干预效果。主要目的是评估使用规范策略提供 HIV 检测的接触者是否会比使用标准策略提供检测的接触者更频繁地接受 HIV 检测。大约 198 个家庭将通过乌干达坎帕拉的三个公共卫生机构进行登记。家庭将被随机分配接受规范或标准策略，并由分配到该策略的社区卫生工作者 (CHW) 进行拜访。年龄≥15 岁的合格接触者将接受可选的免费家庭 HIV 检测。主要结果，即接受艾滋病毒检测的接触者比例，将由社区卫生工作者进行评估，并使用意向治疗方法进行分析。次要结果将是艾滋病毒耻辱感的变化、结核病耻辱感的变化、艾滋病毒耻辱感对艾滋病毒检测的影响、结核病耻辱感对艾滋病毒检测的影响以及接受艾滋病毒检测的首次邀请接触者的比例。结果将为提供艾滋病毒检测的新的、可扩展的策略提供信息。这项研究得到了耶鲁大学人体调查委员会 (2000024852)、麦克雷雷大学公共卫生学院机构审查委员会 (661) 和乌干达国家科学技术委员会 (HS2567) 的批准。所有参与者，包括患者及其家庭接触者，都将提供口头知情同意。结果将提交给同行评审期刊，并分发给国家利益相关者，包括政策制定者和受影响社区的代表。 ClinicalTrials.gov 标识符：NCT05124665。
HIV status awareness is important for household contacts of patients with tuberculosis (TB). Home HIV testing during TB contact investigation increases HIV status awareness. Social interactions during home visits may influence perceived stigma and uptake of HIV testing. We designed an intervention to normalise and facilitate uptake of home HIV testing with five components: guided selection of first tester; prosocial invitation scripts; opt-out framing; optional sharing of decisions to test; and masking of decisions not to test. We will evaluate the intervention effect in a household-randomised controlled trial. The primary aim is to assess whether contacts offered HIV testing using the norming strategy will accept HIV testing more often than those offered testing using standard strategies. Approximately 198 households will be enrolled through three public health facilities in Kampala, Uganda. Households will be randomised to receive the norming or standard strategy and visited by a community health worker (CHW) assigned to that strategy. Eligible contacts ≥15 years will be offered optional, free, home HIV testing. The primary outcome, proportion of contacts accepting HIV testing, will be assessed by CHWs and analysed using an intention-to-treat approach. Secondary outcomes will be changes in perceived HIV stigma, changes in perceived TB stigma, effects of perceived HIV stigma on HIV test uptake, effects of perceived TB stigma on HIV test uptake and proportions of first-invited contacts who accept HIV testing. Results will inform new, scalable strategies for delivering HIV testing. This study was approved by the Yale Human Investigation Committee (2000024852), Makerere University School of Public Health Institutional Review Board (661) and Uganda National Council on Science and Technology (HS2567). All participants, including patients and their household contacts, will provide verbal informed consent. Results will be submitted to a peer-reviewed journal and disseminated to national stakeholders, including policy-makers and representatives of affected communities. ClinicalTrials.gov Identifier: NCT05124665.
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家庭艾滋病毒咨询和测试：乌干达东部的客户经验和看法。
影响因子：
4.5
作者：
Kyaddondo D;Wanyenze RK;Kinsman J;Hardon A
通讯作者：
Hardon A
实际与感知的艾滋病毒测试规范和个人艾滋病毒测试吸收：乌干达农村的横断面，基于人群的研究。
影响因子：
4.4
作者：
Perkins JM;Nyakato VN;Kakuhikire B;Mbabazi PK;Perkins HW;Tsai AC;Subramanian SV;Christakis NA;Bangsberg DR
通讯作者：
Bangsberg DR
影响因子：
5.4
作者：
Daftary, Amrita
通讯作者：
Daftary, Amrita
DOI：
10.1080/09540121.2014.882488
发表时间：
2014-08-03
影响因子：
1.7
作者：
Wynne, Ashley;Richter, Solina;Kipp, Walter
通讯作者：
Kipp, Walter
影响因子：
4.9
作者：
Tumwesigye, Elioda;Wana, Goodwill;Nuwaha, Fred
通讯作者：
Nuwaha, Fred