Efficient cell chatting between embryo and uterus ensures embryo implantation†.
Efficient cell chatting between embryo and uterus ensures embryo implantation†.
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DOI：
10.1093/biolre/ioac135
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发表时间：
2022-07-25
影响因子：
3.6
通讯作者：
中科院分区：
文献类型：
--
作者：
胚胎植入是女性生殖过程中最热门的话题之一，因为它是母体子宫与发育中的胚胎之间的第一次对话，其中断将导致不良的妊娠结局。随着技术的不断进步，利用遗传学和分子生物学手段对胚胎着床的机制进行了深入研究，取得了许多成果。近几十年来，随着概念的提出，人们对着床胚胎与受体子宫之间的相互通讯机制有了更深入的了解。受这些令人满意的进展的启发，我们的目的是总结和回顾目前的进展，从胚胎植入的角度，以减轻不孕症，提高胎儿健康，并改善避孕设计的关键决定因素之间的相互沟通母体子宫和胚胎信号。本文从胚胎着床的角度，对母体子宫与胚胎信号相互作用的关键决定因素进行综述，旨在促进胚胎着床机制的研究，最终缓解不孕症，提高胎儿健康水平，改进避孕设计。
Embryo implantation is one of the hottest topics during female reproduction since it is the first dialogue between maternal uterus and developing embryo whose disruption will contribute to adverse pregnancy outcome. Numerous achievements have been made to decipher the underlying mechanism of embryo implantation by genetic and molecular approaches accompanied with emerging technological advances. In recent decades, raising concepts incite insightful understanding on the mechanism of reciprocal communication between implantation competent embryos and receptive uterus. Enlightened by these gratifying evolvements, we aim to summarize and revisit current progress on the critical determinants of mutual communication between maternal uterus and embryonic signaling on the perspective of embryo implantation to alleviate infertility, enhance fetal health, and improve contraceptive design. We revisit the progress on the critical determinants of mutual communication between maternal uterus and embryonic signaling on the perspective of embryo implantation and aim to advance the mechanism study of embryo implantation and ultimately alleviate infertility, enhance fetal health, and improve contraceptive design.
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影响因子：
82.9
作者：
Cha J;Sun X;Dey SK
通讯作者：
Dey SK
影响因子：
64.5
作者：
Dekker J;Mirny L
通讯作者：
Mirny L
影响因子：
33.5
作者：
Fan Y;Min Z;Alsolami S;Ma Z;Zhang E;Chen W;Zhong K;Pei W;Kang X;Zhang P;Wang Y;Zhang Y;Zhan L;Zhu H;An C;Li R;Qiao J;Tan T;Li M;Yu Y
通讯作者：
Yu Y
DOI：
10.1074/jbc.m110.197202
发表时间：
2011-02-11
期刊：
The Journal of biological chemistry
影响因子：
--
作者：
Chen Q;Zhang Y;Peng H;Lei L;Kuang H;Zhang L;Ning L;Cao Y;Duan E
通讯作者：
Duan E
影响因子：
64.8
作者：
Bulut-Karslioglu, Aydan;Biechele, Steffen;Jin, Hu;Macrae, Trisha A.;Hejna, Miroslav;Gertsenstein, Marina;Song, Jun S.;Ramalho-Santos, Miguel
通讯作者：
Ramalho-Santos, Miguel