Using connectome-based models of working memory to predict emotion regulation in older adults.
Using connectome-based models of working memory to predict emotion regulation in older adults.
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DOI：
10.1093/scan/nsad036
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发表时间：
2023-07-25
影响因子：
4.2
通讯作者：
Prakash, Ruchika S.
中科院分区：
文献类型：
--
作者：
Fisher, Megan E.;Teng, James;Gbadeyan, Oyetunde;Prakash, Ruchika S.
老年人的特点是增强的情绪健康可能导致更大的依赖适应性情绪调节策略。然而，并不是所有的老年人都表现出情绪健康的增加，而是依赖于适应不良的情绪调节策略。工作记忆（WM）及其潜在的神经回路是与年龄相关的策略偏好变化的一个重要调节者。因此，WM背后的神经完整性的个体差异可以预测老年人的情绪调节策略偏好。我们的研究使用全脑WM网络-来自年轻人使用基于连接组的预测建模-预测WM的性能和接受策略的使用在健康的老年人。老年人（N = 110）完成了基线评估，作为随机对照试验的一部分，检查身心干预对健康老龄化的影响。我们的研究结果表明，工作记忆网络预测工作记忆的准确性，但不接受使用或困难的情绪调节在老年人。WM性能的个体差异，但不是WM网络，调节图像强度和接受使用之间的关系。这些研究结果强调，强大的WM神经标记物推广到一个独立的健康老年人样本，但可能不会推广到认知领域以外的预测情绪为基础的行为。
Older adulthood is characterized by enhanced emotional well-being potentially resulting from greater reliance on adaptive emotion regulation strategies. However, not all older adults demonstrate an increase in emotional well-being and instead rely on maladaptive emotion regulation strategies. An important moderator of age-related shifts in strategy preferences is working memory (WM) and its underlying neural circuitry. As such, individual differences in the neural integrity underlying WM may predict older adults’ emotion regulation strategy preferences. Our study used whole-brain WM networks—derived from young adults using connectome-based predictive modeling—to predict WM performance and acceptance strategy use in healthy older adults. Older adults (N = 110) completed baseline assessments as part of a randomized controlled trial examining the impact of mind-body interventions on healthy aging. Our results revealed that the WM networks predicted WM accuracy but not acceptance use or difficulties in emotion regulation in older adults. Individual differences in WM performance, but not WM networks, moderated relationships between image intensity and acceptance use. These findings highlight that robust neural markers of WM generalize to an independent sample of healthy older adults but may not generalize beyond cognitive domains to predict emotion-based behaviors.
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DOI：
10.1073/pnas.0504136102
发表时间：
2005-07-05
影响因子：
11.1
作者：
Fox, MD;Snyder, AZ;Raichle, ME
通讯作者：
Raichle, ME
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影响因子：
7.7
作者：
Crittenden BM;Mitchell DJ;Duncan J
通讯作者：
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影响因子：
4.8
作者：
Geerligs L;Tsvetanov KA;Cam-Can;Henson RN
通讯作者：
Henson RN
影响因子：
2.1
作者：
Jaeggi, Susanne M.;Buschkuehl, Martin;Meier, Beat
通讯作者：
Meier, Beat
影响因子：
3.7
作者：
Buhle, Jason T.;Silvers, Jennifer A.;Ochsner, Kevin N.
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Ochsner, Kevin N.