5‐hydroxytryptamine in normal human platelets
5‐hydroxytryptamine in normal human platelets
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正常人血小板中的 5-羟色胺
DOI：
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发表时间：
1955
期刊：
影响因子：
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通讯作者：
R. S. Stacey
中科院分区：
文献类型：
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作者：
R. Hardisty;R. S. Stacey
Humphrey & Jaques (1954) 和 Udenfriend & Weissbach (1954) 表明，血液中的 5-羟色胺 (HT) 几乎完全由血小板携带。这表明，通过研究HT在血液疾病中的浓度和分布，特别是在血小板形成和功能异常的疾病中，可以揭示HT的生理功能。一些初步研究表明，事实上，在某些疾病中，这种物质的全血和血小板含量都显着降低。这里报道的工作，其部分内容已经出现（Hardisty & Stacey，1955），其目的是建立一种可靠的估计血液中 HT 的方法，确定正常人类受试者的标准，并开发一种评估血小板吸收 HT 能力的方法。
It has been shown by Humphrey & Jaques (1954) and by Udenfriend & Weissbach (1954) that 5-hydroxytryptamine (HT) in the blood is carried almost entirely by platelets. This suggested that light might be thrown on the physiological function of HT by an inquiry into its concentration and distribution in blood disorders, especially those in which platelet formation and function are abnormal. Some preliminary work showed that there is, in fact, a very marked reduction in both the whole blood and platelet content of this substance in certain diseases. The work reported here, a preliminary account of part of which has already appeared (Hardisty & Stacey, 1955), was carried out in order to establish a reliable method for estimating HT in blood, to determinine standards for normal human subjects and to develop a method for evaluating the ability of platelets to absorb HT.
唾液分泌物：发作性睡病和中枢神经系统兴奋剂。
影响因子：
7.6
作者：
Nordgarden,H;Lamkin,M;Oppenheim,FG;Storhaug,K;Jensen,JL
通讯作者：
Jensen,JL