Is Who you Ask Important? Concordance Between Survey and Registry Data on Medication Use Among Self- and Proxy-Respondents in the Longitudinal Study of Aging Danish Twins and the Danish 1905-Cohort Study.
Is Who you Ask Important? Concordance Between Survey and Registry Data on Medication Use Among Self- and Proxy-Respondents in the Longitudinal Study of Aging Danish Twins and the Danish 1905-Cohort Study.
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你问谁很重要吗？在对丹麦双胞胎衰老的纵向研究和丹麦1905-Cohort研究的纵向研究中，关于自我和代表响应中药物使用的调查数据和注册表数据之间的一致性。
DOI：
10.1093/gerona/gly104
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发表时间：
2019-04-23
期刊：
影响因子：
--
通讯作者：
Wastesson JW
中科院分区：
文献类型：
--
作者：
Oksuzyan A;Sauer T;Gampe J;Höhn A;Wod M;Christensen K;Wastesson JW
This study investigates the accuracy of the reporting of medication use by proxy- and self-respondents, and it compares the prognostic value of the number of medications from survey and registry data for predicting mortality across self- and proxy-respondents. The study is based on the linkage of the Longitudinal Study of Aging Danish Twins and the Danish 1905–Cohort Study with the Danish National Prescription Registry. We investigated the concordance between survey and registry data, and the prognostic value of medication use when assessed using survey and registry data, to predict mortality for self- and proxy-respondents at intake surveys. Among self-respondents, the agreement was moderate (κ = 0.52–0.58) for most therapeutic groups, whereas among proxy-respondents, the agreement was low to moderate (κ = 0.36–0.60). The magnitude of the relative differences was, generally, greater among proxies than among self-respondents. Each additional increase in the total number of medications was associated with 7%–8% mortality increase among self- and 4%–6% mortality increase among proxy-respondents in both the survey and registry data. The predictive value of the total number of medications estimated from either data source was lower among proxies (c-statistic = 0.56–0.58) than among self-respondents (c-statistic = 0.74). The concordance between survey and registry data regarding medication use and the predictive value of the number of medications for mortality were lower among proxy- than among self-respondents.
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影响因子：
5.4
作者：
NELSON, LM;LONGSTRETH, WT;VANBELLE, G
通讯作者：
VANBELLE, G
影响因子：
7.2
作者：
Richardson, Kathryn;Kenny, Rose Anne;Bennett, Kathleen
通讯作者：
Bennett, Kathleen
影响因子：
12.7
作者：
Todorov, A;Kirchner, C
通讯作者：
Kirchner, C
影响因子：
5.3
作者：
Hjelmborg, JV;Iachine, I;Christensen, K
通讯作者：
Christensen, K
影响因子：
2.6
作者：
Wastesson, Jonas W.;Rasmussen, Lotte;Pottegard, Anton
通讯作者：
Pottegard, Anton