An innovative biologic recycling process of leukoreduction filters to produce active human antimicrobial peptides
An innovative biologic recycling process of leukoreduction filters to produce active human antimicrobial peptides
复制标题
一种创新的白细胞减少过滤器生物回收工艺，用于生产活性人类抗菌肽
作者：
Ludivine Vossier;F. Leon;Cécile Bachelier;H. Marchandin;S. Lehmann;J. Leonetti;K. Brodolin;J. Coste;C. Fournier
人中性粒细胞多肽(HNPs)1~3是中性粒细胞嗜天青颗粒的主要抗菌肽。它们代表着先天免疫系统的一个重要分支。由于它们的组成和三个二硫键的存在，通过化学合成和重组技术生产它们的成本很高，而且受到技术限制。
Human neutrophil peptides (HNPs) 1 to 3 are the major antimicrobial peptides of the azurophilic granules of neutrophils. They represent an important arm of the innate immune system. Their production by chemical synthesis and recombinant technologies is expensive and limited by technical constraints due to their composition and the presence of three disulfide bonds.
DOI：
10.1016/j.ijantimicag.2011.05.004
发表时间：
2011-09
影响因子：
10.8
作者：
Brogden NK;Brogden KA
通讯作者：
Brogden KA
影响因子：
15.9
作者：
LEHRER, RI;BARTON, A;SELSTED, ME
通讯作者：
SELSTED, ME