Magnetic resonance imaging correlates of neuropsychological impairment in multiple sclerosis.
Magnetic resonance imaging correlates of neuropsychological impairment in multiple sclerosis.
复制标题
磁共振成像与多发性硬化症的神经心理损伤相关。
DOI:
10.1176/jnp.4.2.152
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发表时间:
1992
期刊:
影响因子:
--
通讯作者:
R. McGhee
中科院分区:
文献类型:
--
作者:
S. Huber;R. Bornstein;K. Rammohan;J. A. Christy;D. Chakeres;R. McGhee
The authors examined whether specific neuropsychological abnormalities in multiple sclerosis (MS) are associated with focal lesion areas detected by MRI. Lesion area, regardless of distribution, correlated with performance on the vast majority of neuropsychological procedures. No significant difference appeared between groups with normal/mild and moderate overall cognitive impairment on any of the MRI measures. However, patients with severe cognitive impairment had greater lesion area, regardless of location, and had significant atrophy of the corpus callosum compared with the other two groups. These results suggest that severe atrophy of the corpus callosum reflects global disease and provides a relatively focal morphological marker of severe cognitive impairment in MS.
影响因子:
--
作者:
Rao,SM;Bernardin,L;Leo,GJ;Ellington,L;Ryan,SB;Burg,LS
通讯作者:
Burg,LS
影响因子:
8.9
作者:
Stewart,JM;Houser,OW;BakerJr,HL;O'Brien,PC;Rodriguez,M
通讯作者:
Rodriguez,M
DOI:
--
发表时间:
1985
期刊:
AJNR. American journal of neuroradiology
影响因子:
--
作者:
Jackson,JA;Leake,DR;Schneiders,NJ;Rolak,LA;Kelley,GR;Ford,JJ;Appel,SH;Bryan,RN
通讯作者:
Bryan,RN