Dyspnea during exercise and voluntary hyperpnea in women with obesity.

Dyspnea during exercise and voluntary hyperpnea in women with obesity.
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DOI:
10.1016/j.resp.2021.103638
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发表时间:
2021-05
影响因子:
2.3
通讯作者:
Babb TG
Babb TG
中科院分区:
医学4区
文献类型:
--
作者:
Spencer MD;Balmain BN;Bernhardt V;Wilhite DP;Babb TG

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研究了肥胖女性在恒定负荷和递增负荷运动以及自主呼吸过度(EVH)过程中呼吸急促(RBP)的时间反应。在6分钟的恒定负荷(60 W)循环后,34名女性评定RPB≥4(+DOE),22名女性评定RPB≤2(−DOE)。两组均以40和60 L/min的速度完成递增循环试验和EVH试验;每分钟递增循环和每次EVH试验结束时评估RPB。在恒定负荷(+DOE:R2=0.86; −DOE:R2=0.82)和增量(+DOE:R2=0.91; −DOE:R2 =0.92)运动中,RPB随通气而增加,但+DOE的y轴截距大于−DOE(60 W:-0.16 ±1.53 vs-0.73 ±0.55;增量:-0.50 ±1.40 vs-1.71 ±0.84)。尽管通气匹配,但+DOE组的RPB在基线(0.97±1.14 vs 0.14±0.28)、EVH期间40 L/min(2.50±1.43 vs 0.98±0.91)和60 L/min(3.94±2.19 vs 2.07±1.32)时更大。这些结果表明,尽管RPB和运动期间的通气和自主呼吸过度之间存在线性相关性,但与−DOE相比,+DOE中给定呼吸需求下的呼吸急促感知增强。
Temporal responses of ratings of perceived breathlessness (RBP) during constant-load and incremental exercise, and during voluntary hyperpnea (EVH) were examined in obese women. Following 6min of constant-load (60W) cycling, 34 women rated RPB≥4 (+DOE) and 22 women rated RPB≤2 (−DOE). Both groups completed an incremental cycling test and an EVH test at 40 and 60L/min; RPB was assessed each minute of incremental cycling and at the end of each EVH trial. RPB increased with ventilation during constant-load (+DOE: R2=0.86; −DOE: R2=0.82) and incremental (+DOE: R2=0.91; −DOE: R2=0.92) exercise, but +DOE had a greater y-intercept than −DOE (60W: −0.16±1.53 vs −0.73±0.55; incremental: −0.50±1.40 vs −1.71±0.84). Despite matching ventilation, RPB was greater in +DOE at baseline (0.97±1.14 vs 0.14±0.28), 40L/min (2.50±1.43 vs 0.98±0.91), and 60L/min (3.94±2.19 vs 2.07±1.32) during EVH. These findings show that despite linear associations between RPB and ventilation during exercise and voluntary hyperpnea, breathlessness perception at a given ventilatory demand is heightened in +DOE compared with −DOE.
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发表时间: 2005-09-01
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