American Geriatrics Society updated Beers Criteria for potentially inappropriate medication use in older adults.

American Geriatrics Society updated Beers Criteria for potentially inappropriate medication use in older adults.
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DOI:
10.1111/j.1532-5415.2012.03923.x
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发表时间:
2012-04
影响因子:
6.3
通讯作者:
American Geriatrics Society 2012 Beers Criteria Update Expert Panel
American Geriatrics Society 2012 Beers Criteria Update Expert Panel
中科院分区:
医学1区
文献类型:
--
作者:
American Geriatrics Society 2012 Beers Criteria Update Expert Panel

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尽管有证据表明,在老年人中使用潜在不适当药物(PIMs)的结果不佳,但仍在为最脆弱的老年人开具和使用潜在不适当药物(PIMs)作为一线治疗。项目管理计划现已成为政策和实践的一个组成部分,并被纳入若干质量措施。该项目的具体目的是通过对老年人药物相关问题和药物不良事件(ADEs)的证据进行全面、系统的审查和分级,更新以前的比尔斯标准。这项工作是在美国老年医学会(AGS)的支持下完成的,由11名老年护理和药物治疗专家组成的跨学科小组运用改进的德尔菲法进行系统评价和评分,以达成更新的2012年AGS Beers标准的共识。53种药物或药物类别包含了最终更新的标准,分为三类:老年人可能不适当的药物和应避免的药物类别,老年人可能不适当的药物和应避免的药物类别,所列药物可能加剧某些疾病和综合征,最后是老年人应谨慎使用的药物。这一更新具有很大的优势,包括采用循证方法,采用医学研究所的标准,并建立伙伴关系,定期更新《标准》。经过深思熟虑的标准应用将允许(a)更密切地监测药物使用,(b)应用实时电子处方和干预措施来减少老年人的ade,以及(c)更好的患者预后。
Potentially inappropriate medications (PIMs) continue to be prescribed and used as first-line treatment for the most vulnerable of older adults, despite evidence of poor outcomes from the use of PIMs in older adults. PIMs now form an integral part of policy and practice and are incorporated into several quality measures. The specific aim of this project was to update the previous Beers Criteria using a comprehensive, systematic review and grading of the evidence on drug-related problems and adverse drug events (ADEs) in older adults. This was accomplished through the support of The American Geriatrics Society (AGS) and the work of an interdisciplinary panel of 11 experts in geriatric care and pharmacotherapy who applied a modified Delphi method to the systematic review and grading to reach consensus on the updated 2012 AGS Beers Criteria. Fifty-three medications or medication classes encompass the final updated Criteria, which are divided into three categories: potentially inappropriate medications and classes to avoid in older adults, potentially inappropriate medications and classes to avoid in older adults with certain diseases and syndromes that the drugs listed can exacerbate, and finally medications to be used with caution in older adults. This update has much strength, including the use of an evidence-based approach using the Institute of Medicine standards and the development of a partnership to regularly update the Criteria. Thoughtful application of the Criteria will allow for (a) closer monitoring of drug use, (b) application of real-time e-prescribing and interventions to decrease ADEs in older adults, and (c) better patient outcomes.
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