Use of geriatric assessment for older adults in the oncology setting: a systematic review.
Use of geriatric assessment for older adults in the oncology setting: a systematic review.
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在肿瘤学环境中对老年人的老年评估使用：系统评价。
DOI：
10.1093/jnci/djs285
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发表时间：
2012-08-08
期刊：
影响因子：
--
通讯作者：
Alibhai SM
中科院分区：
文献类型：
--
作者：
Puts MT;Hardt J;Monette J;Girre V;Springall E;Alibhai SM
老年评估是一个多学科的诊断过程，评估老年人的医疗，心理，社会和功能能力。尚未对老年评估在肿瘤学中的应用进行系统评价。本系统性综述的目的是：1）概述肿瘤学环境中使用的所有老年评估工具; 2）检查这些工具的可行性和心理测量学特性; 3）系统评价老年评估在预测或改变结局（包括对治疗决策、治疗毒性和死亡率的影响）方面的有效性。我们检索了Medline、Embase、Psychinfo、Cinahl和科克伦图书馆1996年1月1日至2010年11月16日期间以英语、法语、荷兰语或德语发表的文章，报告了评估老年评估工具可行性或有效性的横断面、纵向、干预性或观察性研究。使用相关质量评估框架评价文章质量。我们确定了83篇文章，报告了73项研究。大多数研究的质量为较差至中等。11项研究检查了所使用的老年评估工具的心理测量特性或诊断准确性。评估一般需要10- 45分钟。最常完成的老年评估是描述患者的健康和功能状态。在9项研究中，6项与治疗毒性相关，在16项研究中，8项与死亡率相关。在研究老年评估对癌症治疗决策的影响的四项研究中，两项发现老年评估影响了40%-50%的治疗决策。在肿瘤学环境中进行老年评估是可行的，并且某些领域与不良结局相关。然而，老年评估影响治疗决策的证据有限。需要进一步研究老年评估对治疗决策和结果的有效性。
Geriatric assessment is a multidisciplinary diagnostic process that evaluates the older adult’s medical, psychological, social, and functional capacity. No systematic review of the use of geriatric assessment in oncology has been conducted. The goals of this systematic review were: 1) to provide an overview of all geriatric assessment instruments used in the oncology setting; 2) to examine the feasibility and psychometric properties of those instruments; and 3) to systematically evaluate the effectiveness of geriatric assessment in predicting or modifying outcomes (including the impact on treatment decision making, toxicity of treatment, and mortality). We searched Medline, Embase, Psychinfo, Cinahl, and the Cochrane Library for articles published in English, French, Dutch, or German between January 1, 1996, and November 16, 2010, reporting on cross-sectional, longitudinal, interventional, or observational studies that assessed the feasibility or effectiveness of geriatric assessment instruments. The quality of articles was evaluated using relevant quality assessment frameworks. We identified 83 articles that reported on 73 studies. The quality of most studies was poor to moderate. Eleven studies examined psychometric properties or diagnostic accuracy of the geriatric assessment instruments used. The assessment generally took 10–45min. Geriatric assessment was most often completed to describe a patient’s health and functional status. Specific domains of geriatric assessment were associated with treatment toxicity in 6 of 9 studies and with mortality in 8 of 16 studies. Of the four studies that examined the impact of geriatric assessment on the cancer treatment decision, two found that geriatric assessment impacted 40%–50% of treatment decisions. Geriatric assessment in the oncology setting is feasible, and some domains are associated with adverse outcomes. However, there is limited evidence that geriatric assessment impacted treatment decision making. Further research examining the effectiveness of geriatric assessment on treatment decisions and outcomes is needed.
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影响因子：
6.2
作者：
Chaibi, Pascal;Magne, Nicolas;Spano, Jean-Philippe
通讯作者：
Spano, Jean-Philippe
影响因子：
6.2
作者：
Basso, Umberto;Tonti, Singora;Monfardini, Silvio
通讯作者：
Monfardini, Silvio
影响因子：
2.1
作者：
Bailey, C;Corner, J;Haviland, J
通讯作者：
Haviland, J
影响因子：
8.4
作者：
Clough-Gorr, Kerri M.;Thwin, Soe Soe;Silliman, Rebecca A.
通讯作者：
Silliman, Rebecca A.
接受雄激素剥夺疗法的前列腺癌生化复发老年男性的肥胖、体能缺陷和跌倒： 病例对照研究
影响因子：
2.1
作者：
Bylow, Kathryn;Hemmerich, Joshua;Dale, William
通讯作者：
Dale, William