Dietary Supplementation of Probiotic Lactobacillus acidophilus Modulates Cholesterol Levels, Immune Response, and Productive Performance of Laying Hens.
Dietary Supplementation of Probiotic Lactobacillus acidophilus Modulates Cholesterol Levels, Immune Response, and Productive Performance of Laying Hens.
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DOI：
10.3390/ani10091588
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发表时间：
2020-09-06
期刊：
影响因子：
--
通讯作者：
Moustafa ES
中科院分区：
文献类型：
--
作者：
Alaqil AA;Abbas AO;El-Beltagi HS;El-Atty HKA;Mehaisen GMK;Moustafa ES
鸡蛋为人类的食物和健康提供了相当多的优质营养物质。然而，鸡蛋消费可能会伤害一些人，因为它的胆固醇含量高，与心血管疾病的风险有关。因此，本研究探讨了嗜酸乳杆菌（Lactobacillus acidophilus，LA）作为益生菌添加剂在蛋鸡日粮中对降低蛋黄胆固醇的可能效果，并对蛋鸡的免疫应答和生产性能进行了评价。所获得的结果显示，当在母鸡饮食中补充LA时，LA能够降低母鸡的血浆甘油三酯和胆固醇水平以及肝脏和蛋黄胆固醇。还探讨了LA对产蛋鸡中一些重要的体液和细胞介导的免疫应答的有益作用。这些积极影响导致产蛋鸡生产性能的改善。因此，除了对产蛋鸡的生产性能和健康产生积极影响外，膳食LA补充剂可被推荐为商业低胆固醇鸡蛋生产的营养策略。本研究旨在探讨饲粮中添加嗜酸乳杆菌（LA）对蛋鸡胆固醇水平、免疫功能及生产性能的影响。选用216只40周龄商品代海兰褐壳蛋鸡，随机分为4组（每组18只，重复3次），分别在日粮中添加0（对照）、1 × 109、21 × 109和31 × 109菌落形成单位（CFU）的嗜酸乳杆菌（LA），连续饲喂6周。结果显示，与对照组相比，补充LA的组的血浆甘油三酯、低密度脂蛋白（LDL）和总胆固醇变得更少，而高密度脂蛋白（HDL）胆固醇变得更高。此外，一个显着的减少发生在肝脏和蛋黄胆固醇的LA补充。此外，免疫学参数，包括抗体效价对绵羊红细胞（SRBCs），植物血凝素（PHA）-荆枣肿胀试验，和T-和B-淋巴细胞增殖的蛋鸡补充LA相比，对照组增强。而异嗜性细胞与淋巴细胞（H/L）的比值随着LA的补充而降低，表明处理母鸡的应激条件较低。LA的这些积极作用进一步反映在产蛋鸡的生产性能上，并改善了产蛋量、蛋重、蛋质量和饲料效率。我们的研究结果表明，可以推荐在产蛋鸡饮食中添加LA益生菌，以降低蛋黄胆固醇，对健康和生产性能产生积极影响。
Chicken eggs provide a considerable source of high-quality nutrients for human food and health. However, egg consumption may harm some people for its high contents of cholesterol and association with cardiovascular disease risk. Therefore, we investigated the possible effect of using Lactobacillus acidophilus (LA) as a probiotic additive in the laying hens’ diets on lowering egg-yolk cholesterol and also evaluated the immune responses and the productive performance of laying hens. The obtained results display the ability of LA, when supplemented in hen diets, to decrease the plasma triglycerides and cholesterol levels and the liver and egg yolk cholesterols in the hen. The beneficial effects of LA were also explored on some important humoral and cell-mediated immune responses in the laying hens. These positive effects led to an improvement in the productive performance of laying hens. Therefore, dietary LA supplementation could be recommended as a nutritional strategy for commercial lower-cholesterol egg production in addition to positive impacts on the performance and health of laying hens. This study examines the effect of dietary supplementation with Lactobacillus acidophilus (LA) on the cholesterol levels, immune response, and productive performance of laying hens. A total of 216, 40-week-old, commercial Hy-Line brown chicken layers were randomly assigned into four treatment groups (18 birds × three replicates per group) and fed diet supplemented with 0 (control), 1 × 109, 21 × 109, and 31 × 109 colony forming units (CFUs) of Lactobacillus acidophilus (LA) per kg of feed for six consecutive weeks. Results show that plasma triglycerides, low-density lipoprotein (LDL) and total cholesterols became lesser, while high-density lipoprotein (HDL) cholesterol became higher in LA-supplemented groups compared to the control. In addition, a significant reduction occurred in the liver and egg yolk cholesterol by LA supplementation. Moreover, the immunological parameters including antibody titer against sheep red blood cells (SRBCs), phytohemagglutinin (PHA)-wattle swelling test, and T- & B-lymphocyte proliferation were enhanced in laying hens supplemented with LA compared to the control hens. While the heterophil to lymphocyte (H/L) ratio decreased with LA supplementation, indicating low stress conditions in the treated hens. These positive effects for LA were further reflected on the productive performance of laying hens and improved egg production, egg weight, egg mass, and feed efficiency. Our findings indicate that LA probiotic could be recommended in laying hens’ diets for lowering egg yolk cholesterol with positive impacts on health and performance.
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DOI：
10.1590/s1516-635x2013000100001
发表时间：
2013-03-01
期刊：
Revista Brasileira de Ciência Avícola
影响因子：
--
作者：
Boostani, A;Mahmoodian Fard, H R;Aminafshar, M
通讯作者：
Aminafshar, M
影响因子：
2.5
作者：
Fathi, Moataz;Al-Homidan, Ibrahim;Alsagan, Ahmed
通讯作者：
Alsagan, Ahmed
影响因子：
2
作者：
Koenen, ME;Kramer, J;Boersma, WJA
通讯作者：
Boersma, WJA
影响因子：
0.8
作者：
Jeloka, T K;Dharmatti, G;Pandit, M
通讯作者：
Pandit, M
DOI：
10.5713/ajas.2008.70754
发表时间：
2008-08-01
期刊：
ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES
影响因子：
--
作者：
Khajali, F.;Karimi, S.;Qujeq, D.
通讯作者：
Qujeq, D.