Diurnal and Seasonal Variation of Stroke Incidence in Patients with Cardioembolic Stroke due to Atrial Fibrillation
Diurnal and Seasonal Variation of Stroke Incidence in Patients with Cardioembolic Stroke due to Atrial Fibrillation
复制标题
房颤所致心源性脑卒中患者脑卒中发病率的日间和季节性变化
作者：
K. Spengos;K. Vemmos;G. Tsivgoulis;E. Manios;N. Zakopoulos;M. Mavrikakis;D. Vassilopoulos
不同国家描述了一年中较冷时期发病高峰的季节性变化，以及中风发病单一高峰在早晨的昼夜节律分布。心源性卒中似乎是希腊患者中最常见的卒中亚型。心房颤动被认为是中风的最常见原因。对 300 多名因心房颤动首次发生心源性急性卒中的希腊患者进行的症状发作时间模式分析显示，症状出现呈周期性分布，冬季出现高峰，夏季卒中发生率下降。对该中风亚组中症状发作的日间变化的分析显示，在 08:00–10:00 和 16:00–18:00 之间存在 2 个发病高峰。可以假设第二个频率峰值（尽管较低）与希腊传统的下午睡眠习惯（午睡）之间存在关系。房颤患者的心脏病事件可能集中，特别是在夜间和下午睡眠醒来后的时间间隔内，可能是一个合理的解释，这当然值得进一步研究。
A seasonal variation with an incidence peak during the colder period of the year, as well as a circadian distribution with a single peak of stroke onset in the morning hours are described in various countries. Cardioembolic stroke seems to be the most frequent stroke subtype among Greek patients. Atrial fibrillation is identified as the most frequent cause of stroke. Analysis of the temporal pattern of symptom onset in a series of over 300 Greek patients with first-ever cardioembolic acute stroke due to atrial fibrillation revealed a circannual distribution with a peak during winter and a decline of stroke occurrence during summer. Analysis of the diurnal variation of symptom onset in this stroke subgroup showed a distribution with 2 incidence peaks between 08:00–10:00 and 16:00–18:00. A relation between the second, however lower, frequency peak and the traditional Greek habit of afternoon sleep (siesta) could be assumed. Possible clustering of cardiologic events in patients with atrial fibrillation, especially during the time interval after awakening from night and afternoon sleep, could be a plausible explanation, which certainly deserves to be further investigated.
20 世纪 80 年代中风患者的生存率有所提高。
影响因子：
8.3
作者：
Shahar,E;McGovern,PG;Sprafka,JM;Pankow,JS;Doliszny,KM;Luepker,RV;Blackburn,H
通讯作者：
Blackburn,H
影响因子：
7.7
作者：
Campos, H;Siles, X
通讯作者：
Siles, X
影响因子：
8.3
作者：
KELLYHAYES, M;WOLF, PA;DAGOSTINO, RB
通讯作者：
DAGOSTINO, RB