Coronary active perfusion system can maintain myocardial blood flow and tissue oxygenation.
Coronary active perfusion system can maintain myocardial blood flow and tissue oxygenation.
复制标题
冠状动脉主动灌注系统可以维持心肌血流和组织氧合。
DOI：
10.1016/s1010-7940(02)00339-1
复制
发表时间：
2002
期刊：
影响因子：
--
通讯作者：
T. Kanamori
中科院分区：
文献类型：
--
作者：
H. Kamiya;G. Watanabe;Toshio Doi;Taro Saito;Masao Takahashi;S. Tomita;T. Tsukioka;T. Kanamori
目的：为避免非体外循环冠状动脉搭桥术中的心肌缺血，我们研制了冠状动脉主动灌注系统（CAPS）。方法：16只猪随机分为CAPS灌注组（C组）和单纯冠状动脉阻断组（O组）。结果：C组未观察到室性心律失常，而O组8只猪中有7只发生室性心律失常（P=0.003）。C组血流动力学指标无明显变化，O组血流动力学指标明显恶化。C组心肌血流量、血氧饱和度、血红蛋白+肌红蛋白浓度均维持在基础水平，而O组明显降低（P <0.001）。结论：CAPS是一种可靠的避免冠状动脉闭塞时心肌缺血的方法，可用于非体外循环冠状动脉旁路移植术
Objectives: To avoid myocardial ischemia in off-pump coronary artery bypass, we developed a coronary active perfusion system (CAPS). The purposes of this study were to investigate the changes in myocardial blood flow and tissue oxygenation during CAPS perfusion, and to validate the ventricular arrthymias and hemodynamic deterioration preventing the effect.Methods: Sixteen pigs were divided into a CAPS perfusion group (group C) and a simple coronary occlusion group (group O). The left anterior descending coronary artery was snared in both groups and 30 min of CAPS perfusion was performed in group C.Results: Ventricular arrhythmias were not observed in group C, but occurred in seven out of eight pigs in group O (P=0.003). None of the hemodynamic variables changed in group C, but they deteriorated in group O. Myocardial blood flow, saturation, and hemoglobin plus myoglobin concentration were maintained with a baseline level in group C, but decreased significantly in group O (P≪0.001).Conclusion: CAPS is a reliable method to avoid myocardial ischemia during coronary occlusion and it may be useful for off-pump coronary artery bypass
狗冠状动脉部分和完全闭塞期间的心肌氧合。
影响因子：
20.1
作者：
Parsons,WJ;Rembert,JC;Bauman,RP;Duhaylongsod,FG;GreenfieldJr,JC;Piantadosi,CA
通讯作者：
Piantadosi,CA
心脏预处理的机制：缺血预处理发现十年后。
DOI：
10.1006/jsre.1997.5187
发表时间：
1997
期刊：
The Journal of surgical research.
影响因子：
--
作者：
Meldrum,DR
通讯作者：
Meldrum,DR