BMI modified the association of current smoking with the incidence of hypertension in Chinese population: a 22-year cohort study
BMI modified the association of current smoking with the incidence of hypertension in Chinese population: a 22-year cohort study
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BMI改变了中国人群当前吸烟与高血压发病率的关联：一项22年队列研究
DOI：
10.1186/s12889-020-8428-z
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发表时间：
2020-03
影响因子：
4.5
通讯作者：
Yongjie Chen
中科院分区：
文献类型：
--
作者：
Feifei Yao;Wenfeng Liu;Rencheng Zhao;Guangxiao Li;Xiaojuan Huang;Yongjie Chen
背景关于肥胖和当前吸烟之间的交互作用如何影响高血压的发病率，目前还知之甚少。本研究旨在探讨体重指数对当前吸烟对高血压发病率的影响。方法数据来源于中国健康与营养调查。根据世界卫生组织对中国人的建议，正常体重、超重和肥胖分别以体重指数下限值18.5 kg/m2、23.0 kg/m2和27.5 kg/m来定义。目前的吸烟者被定义为在调查前的最后30 天内至少抽了100支香烟或电子烟、20支雪茄或20根烟斗和其他类型的烟草。高血压定义为收缩压/舒张压 ≥ 140/90 、使用降压药或自我诊断。在女性(P= 0.030)和50-59 年龄组(P= 0.049)中，肥胖与当前吸烟之间存在交互作用。当前吸烟仅是正常体重人群和女性人群高血压发病的显著预测因素(HR：1.119和1.274；HR95%CI：1.013-1.236和1.143-1.415；P= 0.027和0.040)。按年龄分层，当前吸烟仅影响正常体重50~59 年龄段人群高血压的发生(HR：1.356；HR95%CI：1.084~1.697；P= 0.008)。结论当前吸烟仅对正常体重的女性和中年人群高血压发病有显著预测作用，而对超重和肥胖人群以及青年和老年人群无显著影响。
BackgroundThere was little known on how the interaction effect between obesity and current smoking affected the incidence of hypertension. The aim of this study was to investigate how body mass index (BMI) modified the effect of current smoking on the incidence of hypertension.MethodsData were obtained from the China Health and Nutrition Survey (CHNS). According to the WHO recommendations for Chinese people, the normal weight, overweight, and obesity were defined using the BMI cutoff values 18.5 kg/m2, 23.0 kg/m2, and 27.5 kg/m, respectively. Current smokers were defined as having smoked at least 100 cigarettes or electronic cigarettes, 20 cigars, or 20 tobacco pipes and other type of tobacco in the last 30 days preceding the survey. Hypertension was defined as systolic blood pressure (SBP)/ diastolic blood pressure (DBP) ≥ 140/90 mmHg, use of anti-hypertensive medications, or a self-reported diagnosis.ResultsThis study included 12,900 subjects. There were interaction effects between obesity and current smoking in females (P= 0.030) and the 50–59 years group (P= 0.049). Current smoking was a significant predictor of incident hypertension only in the total and female populations with normal weight (HR: 1.119 and 1.274;HR95%CI: 1.013–1.236 and 1.143–1.415; andP= 0.027 and 0.040, respectively). Stratified by age, current smoking affected the development of hypertension only in the 50–59 years subjects with the normal weight (HR: 1.356;HR95%CI: 1.084–1.697; andP= 0.008).ConclusionsCurrent smoking was a significant predictor of incident hypertension only in the female and middle-age populations with normal weight but not in the overweight and obesity as well as the younger and elder populations.
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影响因子：
5.3
作者：
通讯作者：
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影响因子：
3.8
作者：
Lee W;Hwang SH;Choi H;Kim H
通讯作者：
Kim H
影响因子：
1.9
作者：
通讯作者：
--
DOI：
--
发表时间：
2015
期刊：
--
影响因子：
--
作者：
Samantha M. Attard;A. Herring;Bing Zhang;Du Shufa;B. Popkin;P. Gordon-Larsen
通讯作者：
Samantha M. Attard;A. Herring;Bing Zhang;Du Shufa;B. Popkin;P. Gordon-Larsen
DOI：
--
发表时间：
2013
期刊：
--
影响因子：
--
作者：
Maja O’Connor
通讯作者：
Maja O’Connor