Pulmonary perfusion MRI using interleaved variable density sampling and HighlY constrained cartesian reconstruction (HYCR).
Pulmonary perfusion MRI using interleaved variable density sampling and HighlY constrained cartesian reconstruction (HYCR).
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DOI：
10.1002/jmri.24018
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发表时间：
2013-09
影响因子：
4.4
通讯作者：
Nagle, Scott K.
中科院分区：
文献类型：
--
作者：
Wang, Kang;Schiebler, Mark L.;Francois, Christopher J.;Del Rio, A. Munoz;Cornejo, Ma Daniela;Bell, Laura C.;Korosec, Frank R.;Brittain, Jean H.;Holmes, James H.;Nagle, Scott K.
证明在人体中进行单次屏气、非心脏门控、超快、高时空分辨率全胸部MR肺灌注成像的可行性。使用32通道相控阵线圈在3T临床扫描仪上采用所提出的方法对8名受试者（5名男性，3名女性）进行扫描。7例（88%）为健康志愿者，1例为结节病患者志愿者。由3名心胸放射科医师对每例受试者的肺增强峰值期进行重力效应、肺实质增强峰值和伪影严重程度的独立评分。所有研究均由MR技术人员成功执行，无需任何额外培训。平均实质信号非常好，测量值为0.78 ± 0.13（连续量表，0 =“无”→ 1 =“极好”）。运动伪影的平均水平较低，测量值为0.13 ± 0.08（连续量表，0 =“无”→ 1 =“严重”）。在人体中进行单次屏气、非心脏门控、超快、高时空分辨率的全胸部MR肺灌注成像是可行的。
To demonstrate the feasibility of performing single breath-hold, non-cardiac gated, ultrafast, high spatial-temporal resolution whole chest MR pulmonary perfusion imaging in humans. Eight (8) subjects (5 male, 3 female) were scanned with the proposed method on a 3T clinical scanner using a 32-channel phased-array coil. Seven (88%) were healthy volunteers, and one was a patient volunteer with sarcoidosis. The peak lung enhancement phase for each subject was scored for gravitational effect, peak parenchymal enhancement and severity of artifacts by 3 cardiothoracic radiologists independently. All studies were successfully performed by MR technologists without any additional training. Mean parenchymal signal was very good, measuring 0.78 ± 0.13 (continuous scale, 0 = “none” → 1 = “excellent”). Mean level of motion artifacts was low, measuring 0.13 ± 0.08 (continuous scale, 0 = “none” → 1 = “severe”). It is feasible to perform single breath-hold, non-cardiac gated, ultrafast, high spatial-temporal resolution whole chest MR pulmonary perfusion imaging in humans.
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