Young adult mental health and functional outcomes among individuals with remitted, persistent and late-onset ADHD.
Young adult mental health and functional outcomes among individuals with remitted, persistent and late-onset ADHD.
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DOI：
10.1192/bjp.2018.97
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发表时间：
2018-09
期刊：
影响因子：
--
通讯作者：
Arseneault L
中科院分区：
文献类型：
--
作者：
Agnew-Blais JC;Polanczyk GV;Danese A;Wertz J;Moffitt TE;Arseneault L
注意力缺陷多动障碍（ADHD）与许多领域的心理健康问题和功能障碍有关。然而，ADHD的纵向病程如何影响后期功能尚不清楚。解开ADHD发展模式与年轻成人功能的关系。环境风险（E-Risk）纵向双胞胎研究是一项基于人口的队列研究，包括1994-1995年在英格兰和威尔士出生的2，232对双胞胎。我们在5岁、7岁、10岁和12岁的儿童时期以及18岁的青年时期评估了ADHD。我们研究了ADHD从儿童期到青年期的三种发展模式--缓解型、持续性和迟发性ADHD--并将这些组相互比较，并与非ADHD对照组进行了18岁功能的比较。我们还测试了组间差异是否是由于儿童智商、儿童行为障碍或双胞胎之间共有的家庭因素造成的。与没有ADHD的人相比，那些患有ADHD缓解的人在年轻时表现出更差的身体健康和社会经济结果。患有持续性或迟发性ADHD的个体在所有领域都表现出较差的功能，包括心理健康，物质使用，心理社会，身体健康和社会经济结果。总的来说，这些关联不能用儿童智商、儿童品行障碍或共同的家庭因素来解释。儿童ADHD与不良身体健康和社会经济结果的长期关联强调了早期干预的必要性。年轻的成人ADHD表现出更强的关联与较差的心理健康，物质使用和心理社会结果，强调识别和治疗成人ADHD的重要性。没有。
Attention-deficit/hyperactivity disorder (ADHD) is associated with mental health problems and functional impairment across many domains. However, how the longitudinal course of ADHD affects later functioning remains unclear. To disentangle how ADHD developmental patterns are associated with young adult functioning. The Environmental Risk (E-Risk) Longitudinal Twin Study is a population-based cohort of 2,232 twins born in England and Wales in 1994-1995. We assessed ADHD in childhood at ages 5, 7, 10, and 12 and in young adulthood at age 18. We examined three developmental patterns of ADHD from childhood to young adulthood— remitted, persistent, and late–onset ADHD— and compared these groups to one another and to non-ADHD controls on age-18 functioning. We additionally tested whether group differences were due to childhood IQ, childhood conduct disorder, or familial factors shared between twins. Compared to individuals without ADHD, those with remitted ADHD showed poorer physical health and socioeconomic outcomes in young adulthood. Individuals with persistent or late-onset ADHD showed poorer functioning across all domains including mental health, substance use, psychosocial, physical health, and socioeconomic outcomes. Overall, these associations were not explained by childhood IQ, childhood conduct disorder or shared familial factors. Long-term associations of childhood ADHD with adverse physical health and socioeconomic outcomes underscore the need for early intervention. Young adult ADHD showed stronger associations with poorer mental health, substance use, and psychosocial outcomes, emphasizing the importance of identifying and treating adults with ADHD. None.
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影响因子：
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作者：
Klein, Rachel G.;Mannuzza, Salvatore;Olazagasti, Maria A. Ramos;Roizen, Erica;Hutchison, Jesse A.;Lashua, Erin C.;Castellanos, F. Xavier
通讯作者：
Castellanos, F. Xavier
影响因子：
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作者：
Moffitt, TE
通讯作者：
Moffitt, TE
影响因子：
3
作者：
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通讯作者：
Biederman, Joseph
影响因子：
17.7
作者：
Pingault, Jean-Baptiste;Tremblay, Richard E.;Cote, Sylvana M.
通讯作者：
Cote, Sylvana M.
DOI：
10.1089/cpb.2008.0181
发表时间：
2009-02-01
期刊：
CYBERPSYCHOLOGY & BEHAVIOR
影响因子：
--
作者：
Meerkerk, G. -J.;Van Den Eijnden, R. J. J. M.;Garretsen, H. F. L.
通讯作者：
Garretsen, H. F. L.