Nosocomial infection in a newborn intensive care unit (NICU), South Korea.
Nosocomial infection in a newborn intensive care unit (NICU), South Korea.
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DOI：
10.1186/1471-2334-6-103
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发表时间：
2006-06-23
影响因子：
3.7
通讯作者：
Choi EO
中科院分区：
文献类型：
--
作者：
Jeong IS;Jeong JS;Choi EO
本研究旨在了解医院感染（NIs）的发生情况，包括感染率、主要感染部位和常见微生物。参与研究的患者来自韩国一家医院的新生儿重症监护病房（NICU）。通过回顾图表进行回顾性队列研究。研究对象是1月1日至1月1日期间入住NICU、存活时间超过72小时且未转至其他病房的489名新生儿。1995年至1999年9月30日。根据NNIS定义识别NIs。资料用描述性统计进行分析。每100名入院的新生儿中，NIs的累积发病率为30.3例，感染总数为44.6例。发病密度平均为每1000患者日10.2例新生儿和15.1例感染。最常见的感染是肺炎（28%）、血液感染（26%）和结膜炎（22%）。主要病原菌为革兰氏阳性，如金黄色葡萄球菌和凝固酶阴性葡萄球菌。与NI相关的因素是出生体重小于1500 g，小于32孕周，小于8 apgar评分。两组出院情况无统计学差异，但医院感染组住院时间较无感染组长。虽然病原菌的分布与之前的报道相似，但本研究中观察到的医院感染，特别是结膜炎的高发生率值得进一步评估。
This study aimed to determine the occurrence of nosocomial infections (NIs), including infection rates, main infection sites, and common microorganisms. Patients included in the study were taken from a newborn intensive care unit (NICU), in a hospital in South Korea. A retrospective cohort study was performed by reviewing chart. The subjects were 489 neonates who were admitted to the NICU, survived longer than 72 hours, and not transferred to another unit, between Jan. 1. 1995 to Sep. 30, 1999. NIs were identified according to the NNIS definition. Data were analyzed with descriptive statistics. Cumulative incidence rate for NIs was 30.3 neonates out of 100 admissions, with a total of 44.6 infections. The incidence density was average 10.2 neonates and 15.1 infections per 1000 patient days. The most common infections were pneumonia (28%), bloodstream infection (26%), and conjunctivitis (22%). Major pathogens were Gram-positives such as Staphylococcus aureus and coagulase-negative staphylococci. The factors associated with NI was less than 1500 g of birth weight, less than 32 weeks of gestational age, and less than 8 of apgar score. There's no statistical difference in discharge status between two groups, but hospital stay was longer in subjects with nosocomial infection than those without infection. Although the distribution of pathogens was similar to previous reports, a high rate of nosocomial infection and in particular conjunctivitis was observed in this study that merits further evaluation.
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DOI：
10.1038/sj.jp.7211345
发表时间：
2005-08-01
期刊：
Journal of perinatology : official journal of the California Perinatal Association
影响因子：
--
作者：
Efird, Meica M;Rojas, Mario A;Leon, Angela
通讯作者：
Leon, Angela
影响因子：
4.9
作者：
Stover, BH;Shulman, ST;Jarvis, WR
通讯作者：
Jarvis, WR
影响因子：
5.1
作者：
Stoll, BJ;Gordon, T;Wright, LL
通讯作者：
Wright, LL
影响因子：
8
作者：
Makhoul, IR;Sujov, P;Reichman, B
通讯作者：
Reichman, B
影响因子：
4.9
作者：
Nagata, E;Brito, ASJ;Matsuo, T
通讯作者：
Matsuo, T