Impact of the socioeconomic status on the severity and outcome of community-acquired pneumonia among Egyptian children: a cohort study.

Impact of the socioeconomic status on the severity and outcome of community-acquired pneumonia among Egyptian children: a cohort study.
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DOI:
10.1186/2049-9957-3-14
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发表时间:
2014
影响因子:
8.1
通讯作者:
Abdelsalam SM
Abdelsalam SM
中科院分区:
医学1区
文献类型:
--
作者:
Azab SF;Sherief LM;Saleh SH;Elsaeed WF;Elshafie MA;Abdelsalam SM

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社区获得性肺炎 (CAP) 是发展中国家儿童的五大死因之一,每年约造成 300 万人死亡。确定 CAP 可改变的危险因素可能有助于减轻该疾病的负担。在这项研究中,研究了埃及儿童的社会经济地位 (SES) 对 CAP 严重程度和结果的影响。这是一项前瞻性纵向队列研究,纳入了 1,470 名被诊断患有 CAP 的儿童,年龄为 2 至 15 岁(中位年龄 5.4 岁)。 CAP 的诊断基于临床和放射学检查结果。使用结构化调查问卷和患者的医疗记录来收集数据。受试者被分为两组:轻度 CAP 和重度 CAP。比较了社会和人口变量,并进行了多变量逻辑回归分析。多变量分析显示,母亲受教育程度低(OR:3.8;95% CI:2.12 –6.70;P = .0001)、无法获得足够的医疗护理(OR:3.1;95% CI:1.99 –4.88;P = .0001)、家庭收入低(OR:2.2;95% CI:0.99 –4.78;P = .047)和父母吸烟习惯(OR:2.0;95% CI:1.15 –3.55;P = .014)是埃及儿童严重CAP的显着独立预测危险因素。应将针对这些社会人口危险因素的公共卫生措施确定为优先事项,以帮助减轻埃及儿童因严重 CAP 死亡的疾病负担。
Community-acquired pneumonia (CAP) is one of the five leading causes of death among children in developing countries, accounting for approximately three million deaths per year. Identification of the modifiable risk factors of CAP may help to reduce the burden of this disease. In this study, the impact of the socioeconomic status (SES) on the severity and outcome of CAP among Egyptian children was studied. This was a prospective longitudinal cohort study which included 1,470 children diagnosed with CAP, aged two to 15 years (median age 5.4 years). The diagnosis of CAP was based on clinical and radiological findings. A structured questionnaire and the patients’ medical records were used for the data collection. The subjects were divided into two groups: mild and severe CAP. Social and demographic variables were compared, and a multivariate logistic regression analysis was performed. The multivariate analysis showed that a low maternal education level (OR: 3.8; 95% CI: 2.12 –6.70; P = .0001), unavailability of adequate medical care (OR: 3.1; 95% CI: 1.99 –4.88; P = .0001), a low family income (OR: 2.2; 95% CI: 0.99 –4.78; P = .047), and parents’ smoking habits (OR: 2.0; 95% CI: 1.15 –3.55; P = .014) were significant independent predictive risk factors for severe CAP among Egyptian children. Public health measures against these socio-demographic risk factors should be identified as priorities in order to help reduce the disease burden of deaths from severe CAP among Egyptian children.
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