Neuronal Responses to Conspecifics in the Ventral CA1.
Neuronal Responses to Conspecifics in the Ventral CA1.
复制标题
神经元对腹侧 CA1 中同种的反应。
DOI：
10.1016/j.celrep.2019.05.081
复制
发表时间：
2019
期刊：
影响因子：
8.8
通讯作者：
M. Brecht
中科院分区：
文献类型：
--
作者：
R. Rao;Moritz von Heimendahl;Viktor Bahr;M. Brecht
同种识别和歧视是社会交往的一个重要方面。遗传操作涉及CA2子域和腹侧海马在啮齿动物的社会记忆。然而，人们对海马体对社会信号的反应的性质知之甚少。我们的特点是腹侧CA1反应在大鼠，同时与同种跨越间隙。许多细胞表现出不寻常的“社会存在反应”，即，大海拔的射击率，这取决于同种的存在。锐波涟漪活动也增加了同种的存在。这些细胞受到面部触摸和超声波发声的调制。在雄性大鼠中，雌性同种比雄性引起更强的反应。此外，对女性的反应比男性之间更强烈的个别女性之间的差异。细胞对物体的存在几乎没有反应。背侧CA1的反应也显着不同的背侧CA1，其中大多数细胞被同种存在弱抑制。
Conspecific recognition and discrimination is a vital aspect of social interactions. Genetic manipulations have implicated the CA2 sub-field and ventral hippocampus in rodent social memory. However, little is known about the nature of hippocampal responses to social signals. We characterized ventral CA1 responses in rats while interacting with conspecifics across a gap. Many cells showed unusual "social presence responses," i.e., large elevations of firing rates, which were contingent on the presence of a conspecific. Sharp-wave ripple activity was also increased by conspecific presence. The cells were modulated by facial touch and ultrasonic vocalizations. In male rats, female conspecifics evoked stronger responses than males. In addition, responses to females differed more strongly between individual females than between males. Cells showed little response to object presence. Ventral CA1 responses were also markedly different from those of dorsal CA1, where most cells were weakly inhibited by conspecific presence.
影响因子：
7.7
作者：
Rao RP;Mielke F;Bobrov E;Brecht M
通讯作者：
Brecht M
影响因子：
16.2
作者：
Lenschow, Constanze;Brecht, Michael
通讯作者：
Brecht, Michael