Influences of alignment and obesity on knee joint loading in osteoarthritic gait.
Influences of alignment and obesity on knee joint loading in osteoarthritic gait.
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DOI：
10.1016/j.joca.2014.05.013
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发表时间：
2014-07
影响因子：
7
通讯作者：
DeVita, P.
中科院分区：
文献类型：
--
作者：
Messier, S. P.;Pater, M.;Beavers, D. P.;Legault, C.;Loeser, R. F.;Hunter, D. J.;DeVita, P.
To determine the influences of frontal plane knee alignment and obesity on knee joint loads in older, overweight and obese adults with knee osteoarthritis. Cross-sectional investigation of alignment and obesity on knee joint loads using community dwelling older adults (age ≥ 55 yrs.; 27 kg·m−2 ≥ BMI ≤ 41 kg·m−2; 69% female) with radiographic knee osteoarthritis that were a subset of participants (157 out of 454) enrolled in the Intensive Diet and Exercise for Arthritis (IDEA) clinical trial. A higher BMI was associated with greater (p = 0.0006) peak knee compressive forces [overweight, 2411 N (2182, 2639), class 1 obesity, 2772 N (2602, 2943), class 2+ obesity, 2993 N (2796, 3190)] and greater (p = 0.004) shear forces [overweight, 369 N (322, 415), class 1 obesity, 418 N (384, 453), class 2+ obesity, 472 N (432, 513)], independent of alignment, and varus alignment was associated (p < 0.0001) with greater peak external knee adduction moments, independent of BMI [valgus, 18.7 Nm (15.1, 22.4), neutral, 27.7 Nm (24.0, 31.4), varus, 37.0 Nm (34.4, 39.7)]. BMI and alignment were associated with different joint loading measures; alignment was more closely associated with the asymmetry or imbalance of loads across the medial and lateral knee compartments as reflected by the frontal plane external adduction moment, while BMI was associated with the magnitude of total tibio-femoral force. These data may be useful in selecting treatment options for knee osteoarthritis patients (e.g., diet to reduce compressive loads or bracing to change alignment).
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DOI：
10.1002/art.23326
发表时间：
2008-03-15
期刊：
ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH
影响因子：
--
作者：
Hinman, Rana S.;Payne, Craig;Bennell, Kim L.
通讯作者：
Bennell, Kim L.
影响因子：
7
作者：
Baliunas, AJ;Hurwitz, DE;Andriacchi, TP
通讯作者：
Andriacchi, TP
影响因子：
7
作者：
Moyer, R. F.;Birmingham, T. B.;Giffin, J. R.
通讯作者：
Giffin, J. R.
影响因子：
1.9
作者：
Henriksen, Marius;Simonsen, Erik B.;Bliddal, Henning
通讯作者：
Bliddal, Henning
影响因子：
4.2
作者：
D'Lima, Darryl D.;Steklov, Nikolai;Colwell, Clifford W., Jr.
通讯作者：
Colwell, Clifford W., Jr.