In vitro activity of fosfomycin, alone and in combination, against methicillin-resistant Staphylococcus aureus

In vitro activity of fosfomycin, alone and in combination, against methicillin-resistant Staphylococcus aureus
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磷霉素单独和联合使用对耐甲氧西林金黄色葡萄球菌的体外活性

DOI:
10.1128/aac.28.5.689
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发表时间:
1985
影响因子:
4.9
通讯作者:
S. Berk
S. Berk
中科院分区:
医学2区
文献类型:
--
作者:
S. Alvarez;M. Jones;S. Berk

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我们测试了148株耐甲氧西林金黄色葡萄球菌临床分离株对磷霉素单独和与甲氧西林,头孢孟多,庆大霉素,甲氧苄啶,万古霉素组合。磷霉素对148株耐甲氧西林的沙门氏菌有90%的抑制作用。金黄色葡萄球菌菌株,浓度为4微克/ml。在97株(66%)与磷霉素-头孢孟多和69株(46%)与磷霉素-甲氧西林中观察到协同作用。磷霉素与万古霉素、庆大霉素和甲氧苄啶的联合用药在大多数菌株中无差异。
We tested 148 strains of clinical isolates of methicillin-resistant Staphylococcus aureus against fosfomycin alone and in combination with methicillin, cefamandole, gentamicin, trimethoprim, and vancomycin. Fosfomycin inhibited 90% of the 148 methicillin-resistant S. aureus strains at a concentration of 4 micrograms/ml. Synergism was observed in 97 strains (66%) with fosfomycin-cefamandole and in 69 strains (46%) with fosfomycin-methicillin. The combinations of fosfomycin with vancomycin, gentamicin, and trimethoprim were indifferent in most strains.
DOI: 10.1093/infdis/147.1.137
发表时间: 1983
期刊: The Journal of infectious diseases
影响因子: --
作者:
D. Craven;N. Kollisch;Candace R. Hsieh;Michael G. Connolly;W. R. Mccabe
通讯作者: D. Craven;N. Kollisch;Candace R. Hsieh;Michael G. Connolly;W. R. Mccabe
耐甲氧西林金黄色葡萄球菌引起的医院感染的流行病学。
DOI: 10.7326/0003-4819-97-3-309
发表时间: 1982
影响因子: 39.2
作者:
Thompson,RL;Cabezudo,I;Wenzel,RP
通讯作者: Wenzel,RP