Mesh resolution impacts the accuracy of inverse and forward ECG problems

Mesh resolution impacts the accuracy of inverse and forward ECG problems
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网格分辨率影响逆向和正向心电图问题的准确性

DOI:
10.1109/embc.2016.7591615
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发表时间:
2016
期刊:
Proceedings of 2016 IEEE Engineering in Medicine and Biology Society Conference (EMBC
影响因子:
--
通讯作者:
Yang, Hui
Yang, Hui
中科院分区:
--
文献类型:
--
作者:
Yao, Bing;Pei, Shenli;Yang, Hui

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心电图成像(ECGI)已成为一种重要的医学诊断工具,可以帮助科学家无创地研究心电活动。为了了解如何从体电位分布中重构心电活动,已有许多研究工作对心电正、反问题进行了研究。然而,心电逆问题是高度病态的,对误差和噪声非常敏感。因此,有必要研究心电反向和正向问题的敏感性。本文研究了网格分辨率对心电正反问题精度的影响。首先,我们采用边界元法计算体表和心表电位分布之间的关系,并开发了一种求解心电逆正问题的算法。其次,我们实现了算法来解决心电问题在同心球几何和现实的躯干-心脏几何。第三,在不同网格分辨率的条件下,我们评估了我们的解与解析解的相对误差。实验结果表明,在同心圆几何中,将两个球体三角剖分的网格单元从24个增加到400个时,反解的相对误差从30%降低到17%;在真实体心几何中,将心表面三角剖分的网格单元从136个增加到546个时,反解的相对误差从26%降低到16%。
Electrocardiographic imaging (ECGI) has become an important medical diagnosis tool that assists scientists to noninvasively investigate cardiac electric activity. Many previous works have studied the inverse and forward ECG problems to understand how to reconstruct the cardiac electric activity from the body potential distribution. However, the inverse ECG problem is highly ill-conditioned and very sensitive to errors and noises. Thus, there is a need to study the sensitivity of inverse and forward ECG problems. In this paper, we investigated effects of mesh resolution on the accuracy of inverse and forward ECG problems. First, we employed the boundary element method to calculate the relationship between potential distributions on the body and heart surfaces and developed an algorithm to solve inverse and forward ECG problems. Second, we implemented the algorithm to solve the ECG problems in both a concentric spherical geometry and a realistic torso-heart geometry. Third, we evaluated the relative error between our solution and the analytical solution under the condition of different mesh resolutions. Experimental results explicitly show that the relative error in the inverse solution decreased from 30% to 17% when the mesh elements triangulating the two spheres increased from 24 to 400 in the concentric spherical geometry, and that decreased from 26% to 16% when the mesh elements triangulating the heart surface increased from 136 to 546 in the realistic torso-heart geometry.
DOI: --
发表时间: 2014
期刊: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
影响因子: --
作者:
Di Yu;D. Du;Hui Yang;Yi
通讯作者: Yi