Sizing of a vesicle drug formulation by quasi-elastic light scattering and comparison with electron microscopy and ultracentrifugation.
Sizing of a vesicle drug formulation by quasi-elastic light scattering and comparison with electron microscopy and ultracentrifugation.
复制标题
通过准弹性光散射确定囊泡药物制剂的尺寸,并与电子显微镜和超速离心进行比较。
DOI:
--
复制
发表时间:
1987
期刊:
影响因子:
--
通讯作者:
M. Sammons
中科院分区:
文献类型:
--
作者:
M. S. McCracken;M. Sammons
Quasi-elastic light scattering has been used for the sizing of a vesicle formulation. Porcine insulin was encapsulated in a vesicle preparation containing cholesterol, dipalmitoylphosphotidylcholine, digalactosyl digycerides, and dipalmitoylphosphotidylglycerol in a 40:40:15:5 ratio. The measurement requires less than 15 min to obtain mean size and distribution information and can be operated in a quality control environment. Advantages and limitations of quasi-elastic light scattering are described and this method is compared to electron microscopy and ultracentrifugation.
影响因子:
2.9
作者:
Reynolds,JA;Nozaki,Y;Tanford,C
通讯作者:
Tanford,C
DOI:
10.1016/0005-2760(81)90311-8
发表时间:
1981-01-01
期刊:
BIOCHIMICA ET BIOPHYSICA ACTA
影响因子:
--
作者:
ABRA, RM;HUNT, CA
通讯作者:
HUNT, CA