H-InvDB in 2009: extended database and data mining resources for human genes and transcripts.
H-InvDB in 2009: extended database and data mining resources for human genes and transcripts.
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DOI：
10.1093/nar/gkp1020
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发表时间：
2010-01
影响因子：
14.9
通讯作者：
Gojobori T
中科院分区：
文献类型：
--
作者：
Yamasaki C;Murakami K;Takeda J;Sato Y;Noda A;Sakate R;Habara T;Nakaoka H;Todokoro F;Matsuya A;Imanishi T;Gojobori T
我们报告了H-Invitational Database（H-InvDB; http：//www.h-invitational.jp/）中新发布的扩展数据库和数据挖掘资源。H-InvDB是人类基因和转录本的综合注释资源，由两个主视图和六个子数据库组成。最新版本的H-InvDB（6.2版）提供了基于人类全长cDNA和mRNA的43159个人类基因簇中219765个人类转录本的注释。H-InvDB现在提供了几个新的注释功能，例如微阵列探针的映射，新的基因模型，与已知ncRNA的关系以及来自Glycogene数据库的信息。H-InvDB还提供有用的数据挖掘资源-“导航搜索”、“H-InvDB丰富分析工具（HEAT）”和Web服务API。“导航搜索”是一个扩展的搜索系统，通过组合16个不同的搜索选项来实现复杂的搜索。HEAT是一种数据挖掘工具，用于自动识别特定于给定人类基因集的特征。HEAT搜索与整个H-InvDB代表性转录物相比在用户定义的基因集中显著富集的H-InvDB注释。H-InvDB现在具有SOAP和REST的Web服务API，允许在程序中使用H-InvDB数据，为用户提供扩展的数据可访问性。
We report the extended database and data mining resources newly released in the H-Invitational Database (H-InvDB; http://www.h-invitational.jp/). H-InvDB is a comprehensive annotation resource of human genes and transcripts, and consists of two main views and six sub-databases. The latest release of H-InvDB (release 6.2) provides the annotation for 219 765 human transcripts in 43 159 human gene clusters based on human full-length cDNAs and mRNAs. H-InvDB now provides several new annotation features, such as mapping of microarray probes, new gene models, relation to known ncRNAs and information from the Glycogene database. H-InvDB also provides useful data mining resources—‘Navigation search’, ‘H-InvDB Enrichment Analysis Tool (HEAT)’ and web service APIs. ‘Navigation search’ is an extended search system that enables complicated searches by combining 16 different search options. HEAT is a data mining tool for automatically identifying features specific to a given human gene set. HEAT searches for H-InvDB annotations that are significantly enriched in a user-defined gene set, as compared with the entire H-InvDB representative transcripts. H-InvDB now has web service APIs of SOAP and REST to allow the use of H-InvDB data in programs, providing the users extended data accessibility.
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影响因子：
14.9
作者：
Kin T;Yamada K;Terai G;Okida H;Yoshinari Y;Ono Y;Kojima A;Kimura Y;Komori T;Asai K
通讯作者：
Asai K
影响因子：
9.8
作者：
Imanishi T;Itoh T;Suzuki Y;O'Donovan C;Fukuchi S;Koyanagi KO;Barrero RA;Tamura T;Yamaguchi-Kabata Y;Tanino M;Yura K;Miyazaki S;Ikeo K;Homma K;Kasprzyk A;Nishikawa T;Hirakawa M;Thierry-Mieg J;Thierry-Mieg D;Ashurst J;Jia L;Nakao M;Thomas MA;Mulder N;Karavidopoulou Y;Jin L;Kim S;Yasuda T;Lenhard B;Eveno E;Suzuki Y;Yamasaki C;Takeda J;Gough C;Hilton P;Fujii Y;Sakai H;Tanaka S;Amid C;Bellgard M;Bonaldo Mde F;Bono H;Bromberg SK;Brookes AJ;Bruford E;Carninci P;Chelala C;Couillault C;de Souza SJ;Debily MA;Devignes MD;Dubchak I;Endo T;Estreicher A;Eyras E;Fukami-Kobayashi K;Gopinath GR;Graudens E;Hahn Y;Han M;Han ZG;Hanada K;Hanaoka H;Harada E;Hashimoto K;Hinz U;Hirai M;Hishiki T;Hopkinson I;Imbeaud S;Inoko H;Kanapin A;Kaneko Y;Kasukawa T;Kelso J;Kersey P;Kikuno R;Kimura K;Korn B;Kuryshev V;Makalowska I;Makino T;Mano S;Mariage-Samson R;Mashima J;Matsuda H;Mewes HW;Minoshima S;Nagai K;Nagasaki H;Nagata N;Nigam R;Ogasawara O;Ohara O;Ohtsubo M;Okada N;Okido T;Oota S;Ota M;Ota T;Otsuki T;Piatier-Tonneau D;Poustka A;Ren SX;Saitou N;Sakai K;Sakamoto S;Sakate R;Schupp I;Servant F;Sherry S;Shiba R;Shimizu N;Shimoyama M;Simpson AJ;Soares B;Steward C;Suwa M;Suzuki M;Takahashi A;Tamiya G;Tanaka H;Taylor T;Terwilliger JD;Unneberg P;Veeramachaneni V;Watanabe S;Wilming L;Yasuda N;Yoo HS;Stodolsky M;Makalowski W;Go M;Nakai K;Takagi T;Kanehisa M;Sakaki Y;Quackenbush J;Okazaki Y;Hayashizaki Y;Hide W;Chakraborty R;Nishikawa K;Sugawara H;Tateno Y;Chen Z;Oishi M;Tonellato P;Apweiler R;Okubo K;Wagner L;Wiemann S;Strausberg RL;Isogai T;Auffray C;Nomura N;Gojobori T;Sugano S
通讯作者：
Sugano S
影响因子：
14.9
作者：
Bruford, Elspeth A.;Lush, Michael J.;Wright, Mathew W.;Sneddon, Tam P.;Povey, Sue;Birney, Ewan
通讯作者：
Birney, Ewan
影响因子：
14.9
作者：
UniProt Consortium
通讯作者：
UniProt Consortium
影响因子：
14.9
作者：
Safran, M;Chalifa-Caspi, V;Lancet, D
通讯作者：
Lancet, D