The Universal Protein Resource (UniProt) 2009.
The Universal Protein Resource (UniProt) 2009.
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DOI：
10.1093/nar/gkn664
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发表时间：
2009-01
影响因子：
14.9
通讯作者：
UniProt Consortium
中科院分区：
文献类型：
--
作者：
UniProt Consortium
UniProt的使命是为科学界提供一个全面、高质量且可免费获取的蛋白质序列和功能信息资源，这对现代生物学研究至关重要。UniProt由UniProt联盟制作，该联盟由来自欧洲生物信息学研究所、蛋白质信息资源库和瑞士生物信息学研究所的团队组成。核心活动包括在计算分析辅助下对蛋白质序列进行人工注释、序列存档、一个用户友好的UniProt网站以及通过与其他数据库的交叉引用提供额外的增值信息。UniProt由四个主要部分组成，每个部分都针对不同用途进行了优化：UniProt档案库、UniProt知识库、UniProt参考簇以及UniProt宏基因组和环境序列数据库。UniProt联盟在2008年的关键成就之一是在UniProtKB/Swiss - Prot中完成了完整人类蛋白质组的初稿。这种对所有当前已知人类蛋白质编码基因的人工注释表述在UniProt 14.0版本中发布，包含20325个条目。UniProt每三周更新和发布一次，可以在www.uniprot.org上在线搜索或下载。
The mission of UniProt is to provide the scientific community with a comprehensive, high-quality and freely accessible resource of protein sequence and functional information that is essential for modern biological research. UniProt is produced by the UniProt Consortium which consists of groups from the European Bioinformatics Institute, the Protein Information Resource and the Swiss Institute of Bioinformatics. The core activities include manual curation of protein sequences assisted by computational analysis, sequence archiving, a user-friendly UniProt website and the provision of additional value-added information through cross-references to other databases. UniProt is comprised of four major components, each optimized for different uses: the UniProt Archive, the UniProt Knowledgebase, the UniProt Reference Clusters and the UniProt Metagenomic and Environmental Sequence Database. One of the key achievements of the UniProt consortium in 2008 is the completion of the first draft of the complete human proteome in UniProtKB/Swiss-Prot. This manually annotated representation of all currently known human protein-coding genes was made available in UniProt release 14.0 with 20 325 entries. UniProt is updated and distributed every three weeks and can be accessed online for searches or downloaded at www.uniprot.org.
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拟南芥信息资源（TAIR）：基因结构和功能注释。
影响因子：
14.9
作者：
Swarbreck, David;Wilks, Christopher;Lamesch, Philippe;Berardini, Tanya Z.;Garcia-Hernandez, Margarita;Foerster, Hartmut;Li, Donghui;Meyer, Tom;Muller, Robert;Ploetz, Larry;Radenbaugh, Amie;Singh, Shanker;Swing, Vanessa;Tissier, Christophe;Zhang, Peifen;Huala, Eva
通讯作者：
Huala, Eva
影响因子：
3.1
作者：
Gattiker, A;Michoud, K;Bairoch, A
通讯作者：
Bairoch, A
影响因子：
14.9
作者：
Wu, CH;Nikolskaya, A;Barker, WC
通讯作者：
Barker, WC
影响因子：
14.9
作者：
Flicek P;Aken BL;Beal K;Ballester B;Caccamo M;Chen Y;Clarke L;Coates G;Cunningham F;Cutts T;Down T;Dyer SC;Eyre T;Fitzgerald S;Fernandez-Banet J;Gräf S;Haider S;Hammond M;Holland R;Howe KL;Howe K;Johnson N;Jenkinson A;Kähäri A;Keefe D;Kokocinski F;Kulesha E;Lawson D;Longden I;Megy K;Meidl P;Overduin B;Parker A;Pritchard B;Prlic A;Rice S;Rios D;Schuster M;Sealy I;Slater G;Smedley D;Spudich G;Trevanion S;Vilella AJ;Vogel J;White S;Wood M;Birney E;Cox T;Curwen V;Durbin R;Fernandez-Suarez XM;Herrero J;Hubbard TJ;Kasprzyk A;Proctor G;Smith J;Ureta-Vidal A;Searle S
通讯作者：
Searle S
影响因子：
5.8
作者：
Fleischmann, W;Möller, S;Apweiler, R
通讯作者：
Apweiler, R